Different methods have been employed to increase the effectiveness of local treatment. Mechanical methods involve the surgical removal or abrasive grinding of the nail plate [
2,
4]. However, healing after such surgical interference takes a long time, and the probability of reinfection and damage to the nail matrix is high [
5]. Chemical methods involve etching the nail plate due to the destruction of the disulfide, peptide, hydrogen, and polar bonds of keratin. For the destruction of sulfites, hydrogen peroxide, urea, salicylic acid, and different keratolic enzymes are employed. For example, an 88% phenol solution can be utilized, followed by phenol neutralization with ethyl, isopropyl alcohol, alcohol solution of povidone–iodine, 10% NaOH solution, and 20% solution of tartaric acid or 10% phosphoric acid [
6]. Chemical etching takes considerable time to complete [
7], and a weak chemical effect leads to extensive chemical burns and tissue necrosis.