Quantitative Biology

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    2019, Vol.7  No.1

    Arachidonic acid network is a complex system with many pathways to which non-steroidal anti-inflammatroy drugs (NSAIDs) target. However, side effects have always been the disadvantages of these medicines. Using a natural 5-LOX inhibitor HOEC as probe, Yang et al. established a computational model to simulate the flux regulation of arachidonic acid network after HOEC treatment. There is balance in metabolic flux of every pathway, and with the reduce of flux [Detail] ...

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