The integration of generative artificial intelligence and machine learning in healthcare: Current applications and future directions
Muhammad Umar , Laiba Shamim , Imshaal Musharaf , Pakeezah Tabasum , Vani Malhotra , Kanza Farhan , Ayesha Hidayat , Muhammad Waqas , Amna Anwar , Maria Qadri , Shahana Reza
Journal of Intelligent Medicine ›› 2025, Vol. 2 ›› Issue (4) : 179 -192.
Machine learning (ML) and generative artificial intelligence (GAI) in recent years are rapidly revolutionizing the healthcare industry offering improved precision and efficiency of healthcare delivery. The use of these advanced technologies in healthcare such as medical imaging, drug discoveries, predictive analytics, and personalized medicine can diagnose diseases at the earliest, set smarter treatment plans, and improve patient outcomes. ML and generative AI aid in diagnostic accuracy and progress prediction particularly in fields like radiology and oncology, reducing error by 25% compared to traditional methods. Additionally, generative AI-based chatbots like ChatGPT have their role in healthcare through the immediate availability of medical information and assessing urgency and severity of when to seek medical guidance. Despite these advancements, ethical challenges persist such as data privacy, bias in AI algorithms, and lack of transparency. Therefore, techniques like data anonymization and the addition of controlled noise can be applied to remove identification from datasets. This narrative review highlights the implications of integrating ML and generative AI in healthcare affecting clinical practice, patient outcomes, and the broader healthcare system. ML and GAI enhance diagnostic precision and assist healthcare virtually, thereby allowing earlier diagnosis of disease, facilitating personalized treatment strategies, improving patient outcomes, and lowering costs.
diagnostic imaging / generative AI / healthcare / machine learning / virtual health assistants
| [1] |
|
| [2] |
|
| [3] |
|
| [4] |
|
| [5] |
|
| [6] |
|
| [7] |
|
| [8] |
|
| [9] |
|
| [10] |
|
| [11] |
|
| [12] |
|
| [13] |
|
| [14] |
|
| [15] |
The Triple Aim or the Quadruple Aim? Four Points to Help Set Your Strategy | Institute for Healthcare Improvement. 2017. https://www.ihi.org/library/blog/triple-aim-or-quadruple-aim-four-points-help-set-your-strategy |
| [16] |
|
| [17] |
|
| [18] |
|
| [19] |
|
| [20] |
|
| [21] |
|
| [22] |
|
| [23] |
|
| [24] |
|
| [25] |
|
| [26] |
|
| [27] |
|
| [28] |
|
| [29] |
|
| [30] |
|
| [31] |
|
| [32] |
|
| [33] |
|
| [34] |
|
| [35] |
|
| [36] |
|
| [37] |
|
| [38] |
|
| [39] |
|
| [40] |
|
| [41] |
|
| [42] |
|
| [43] |
|
| [44] |
|
| [45] |
|
| [46] |
|
| [47] |
|
| [48] |
|
| [49] |
|
| [50] |
What doctor? Why AI and robotics will define new health. 2016. |
| [51] |
|
| [52] |
|
| [53] |
|
| [54] |
Artificial Intelligence. Risks to Privacy and Democracy. Yale Journal of Law and Technology. Accessed September 17, 2025. https://yjolt.org/artificial-intelligence-risks-privacy-and-democracy |
| [55] |
|
| [56] |
|
| [57] |
|
| [58] |
|
| [59] |
How distributed ledgers can transform healthcare applications. Accessed September 17, 2025. https://ercim-news.ercim.eu/en110/special/how-distributed-ledgers-can-transform-healthcare-applications |
| [60] |
Artificial Intelligence (AI). In: Healthcare and Medical Field. Accessed September 17, 2025. https://www.foreseemed.com/artificial-intelligence-in-healthcare |
| [61] |
Mitigating bias in AI algorithms: ensuring responsible AI. Accessed September 17, 2025. https://blog.leena.ai/mitigating-bias-in-ai/ |
| [62] |
Artificial Intelligence: regulatory landscape. Management solutions. Accessed September 17, 2025. https://www.managementsolutions.com/en/publications-and-events/regulatory-notes/technical-notes-on-regulations/artificial-intelligence-regulatory-landscape |
| [63] |
|
| [64] |
|
| [65] |
|
| [66] |
|
| [67] |
|
| [68] |
Regulation – EU – 2024/1689 – EN – EUR-Lex. Accessed September 17, 2025. https://eur-lex.europa.eu/eli/reg/2024/1689/oj/eng |
| [69] |
Blueprint for an AI Bill of Rights | OSTP. The White House. Accessed September 17, 2025. https://bidenwhitehouse.archives.gov/ostp/ai-bill-of-rights/ |
| [70] |
EU’s AI act: ten facts for organisations in the UK and US – insights – proskauer rose LLP. Accessed September 17, 2025. https://www.proskauer.com/report/eus-ai-act-ten-facts-for-organisations-in-the-uk-and-us?gad_source=1&gad_campaignid=22827212398&gbraid=0AAAAADwYcQ0IIGugCgicGezFuv0hmN2Bw&gclid=Cj0KCQjwuKnGBhD5ARIsAD19RsYPWS_VHJH3hijrCSu3-eMdXkDD_xVQHs-HMg7vPHWUmY8CU76d5kgaAs6EEALw_wcB |
| [71] |
The 2023 AI Index Report. Stanford HAI. Accessed September 17, 2025. https://hai.stanford.edu/ai-index/2023-ai-index-report |
| [72] |
AI Management System—ISO 42001. Accessed September 17, 2025. https://page.bsigroup.com/AI-Management-System-ISO-42001?gad_source=1&gad_campaignid=21346554922&gbraid=0AAAAACeSMaFqnXGAYufk_BSI3-qa1jb90&gclid=Cj0KCQjwuKnGBhD5ARIsAD19RsacKVgyeS5cC_UDe6WdJtIDrAPvsA5hjuKusaBGqd32EwDgIxBW814aAltjEALw_wcB |
| [73] |
PolicyFeed. Accessed September 17, 2025. https://www.policyfeed.com |
| [74] |
|
| [75] |
|
| [76] |
|
| [77] |
|
| [78] |
|
| [79] |
|
| [80] |
|
| [81] |
|
| [82] |
|
| [83] |
|
| [84] |
|
| [85] |
|
| [86] |
|
| [87] |
|
| [88] |
|
| [89] |
|
| [90] |
|
| [91] |
|
2025 The Author(s). Journal of Intelligent Medicine published by John Wiley & Sons Australia, Ltd on behalf of Tianjin University.
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