At present, the non-uniformity correction (NUC) algorithms of IRFPA can be generally divided into two categories, namely reference source based two-point linear correction and scene-based adaptive correction. In recent years, the scene-based correction algorithm has been rapidly developed. More than ten NUC algorithms [
1-
4], such as artificial neural network, constant average statistics, Kalman filter algorithm, algebraic algorithm, etc, have been arisen, and these NUC algorithms generally require to estimate the inter-frame micro-displacement based on the image sequence with varying scene, for the purpose of effectively eliminating non-uniformity noise of IRFPA. On the other hand, the research of high-resolution reconstruction algorithm based on multiple undersampled images also has rapid development [
5-
8], of which the maximum a posteriori (MAP) based high-resolution reconstruction can regularize ill-posed problem [
9,
10], guarantee a unique solution and remove the noise effectively as well as. However, the MAP-based algorithm is been mostly used to aim at visible and infrared image restoration, and has not been related to the NUC. The idea of integrating NUC and multi-frame high-resolution restoration was firstly proposed by Armstrong et al. [
11], who briefly described scene-based NUC techniques to pre-process the data for image registration and high image reconstruction. Later, a scene-based NUC and enhancement algorithm was proposed by Zhao et al. [
12], the core of the proposed framework is a novel registration-based super-resolution method that is bootstrapped by statistical scene-based NUC method.