Research articles

Homeostatic photobiomodulation

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  • 1.Laboratory of Laser Sports Medicine, College of Sports Science, South China Normal University, Guangzhou 510006, China;College of Life, South China Normal University, Guangzhou 510631, China; 2.College of Life, South China Normal University, Guangzhou 510631, China; 3.Laboratory of Laser Sports Medicine, College of Sports Science, South China Normal University, Guangzhou 510006, China; 4.Laboratory Center for Sport Science and Medicine, Guangzhou Institute of Physical Education, Guangzhou 510500, China; 5.School for Information and Optoelectronic Science and Engineering, South China Normal University, Guangzhou 510006, China;

Published date: 05 Mar 2009

Abstract

Photobiomodulation (PBM) is a modulation of laser irradiation or monochromatic light (LI) on biosystems, which stimulates or inhibits biological functions but does not result in irreducible damage. LI might be of low intensity LI (LIL) (about 10 mW/cm2), or moderate intensity LI (MIL) (102―103 mW/cm2). PBM of LIL or MIL (LPBM or MPBM) is studied from the homeostatic viewpoint in this paper. Homeostasis is redefined as the function-specific homeostasis (FSH), a negative-feedback response of a biosystem which maintains the function-specific conditions inside it. PBM is classified into two kinds, the FSH-specific PBM (fPBM) and developmental PBM (dPBM). For fPBM, there is no PBM of LI on the function in FSH, but there is PBM of LI on the function far from FSH. dPBM can disrupt FSH. It can be found that LPBM is an fPBM, and whether MPBM is fPBM or dPBM depends on MIL dose and cell sensitivity. Low level LI therapy is just clinical applications of fPBM, so that it is a cellular rehabilitation.

Cite this article

Timon Chengyi LIU , Ruochun LIU , Ling ZHU , Jianqin YUAN , Min HU , Songhao LIU , . Homeostatic photobiomodulation[J]. Frontiers of Optoelectronics, 2009 , 2(1) : 1 -8 . DOI: 10.1007/s12200-009-0010-3

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