Overcoming ill-posedness of diffuse optical tomography in steady-state domain

Abstract

In recent decades, diffuse optical tomography (DOT) has drawn more and more interest in molecular imaging because of its advantage of large penetration depth in optical image technology. However, ill-posedness problems have dramatically limited this application technique. In this paper, a new method to remove the ill-posedness of DOT is introduced. With a rotating steady-state domain experiment system, by increasing experimental data that could be obtained from any visual angle, four contrast experiments were simulated. It was proved that when the sum of the experiment data is larger than that of the unknown optical coefficient of phantom, ill-posedness would be reduced and the quality of the reconstructed image could be improved.

Keywords

diffuse optical tomography (DOT) / ill-posedness / diffusion approximation / rotation DOT system