Endothelial dysfunction in COVID-19 calls for immediate attention: the emerging roles of the endothelium in inflammation caused by SARS-CoV-2

Weijian Hang , Chen Chen , Xin A. Zhang , Dao Wen Wang

Front. Med. ›› 2021, Vol. 15 ›› Issue (4) : 638 -643.

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Front. Med. ›› 2021, Vol. 15 ›› Issue (4) : 638 -643. DOI: 10.1007/s11684-021-0831-z
LETTER TO FRONTIERS OF MEDICINE
LETTER TO FRONTIERS OF MEDICINE

Endothelial dysfunction in COVID-19 calls for immediate attention: the emerging roles of the endothelium in inflammation caused by SARS-CoV-2

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Abstract

The COVID-19 pandemic has caused numerous deaths around the world. A growing body of evidence points to the important role of overwhelming inflammatory responses in the pathogenesis of COVID-19 and the effectiveness of anti-inflammation therapy against COVID-19 is emerging. In addition to affecting the lungs, COVID-19 can be a severe systemic inflammatory disease that is related to endothelial dysfunction. We are calling for closer attention to endothelial dysfunction in COVID-19 not only for fully revealing the pathogenic mechanism of COVID-19 but also for properly adjusting the strategy of clinical intervention.

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COVID-19 / endothelial dysfunction / inflammation reaction / cytokine storm

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Weijian Hang,Chen Chen,Xin A. Zhang,Dao Wen Wang. Endothelial dysfunction in COVID-19 calls for immediate attention: the emerging roles of the endothelium in inflammation caused by SARS-CoV-2. Front. Med., 2021, 15(4): 638-643 DOI:10.1007/s11684-021-0831-z

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