Cushing’s syndrome during pregnancy caused by adrenal cortical adenoma: a case report and literature review

Wei Wang , Fengyi Yuan , Dan Xu

Front. Med. ›› 2015, Vol. 9 ›› Issue (3) : 380 -383.

PDF (89KB)
Front. Med. ›› 2015, Vol. 9 ›› Issue (3) : 380 -383. DOI: 10.1007/s11684-015-0407-x
CASE REPORT
CASE REPORT

Cushing’s syndrome during pregnancy caused by adrenal cortical adenoma: a case report and literature review

Author information +
History +
PDF (89KB)

Abstract

Cushing’s syndrome (CS) during pregnancy is a rare condition with significant maternal and fetal complications. A case of CS during the third trimester of pregnancy secondary to adrenocortical adenoma was reported. Literature review revealed the disadvantages of different treatments in this period. Besides the conservative treatment, surgery is recommended for CS during the third trimester of pregnancy secondary to adrenal adenoma, if an experienced surgeon is available.

Keywords

Cushing’s syndrome / pregnancy / adrenocortical adenoma

Cite this article

Download citation ▾
Wei Wang, Fengyi Yuan, Dan Xu. Cushing’s syndrome during pregnancy caused by adrenal cortical adenoma: a case report and literature review. Front. Med., 2015, 9(3): 380-383 DOI:10.1007/s11684-015-0407-x

登录浏览全文

4963

注册一个新账户 忘记密码

References

[1]

Lekarev O, New MI. Adrenal disease in pregnancy. Best Pract Res Clin Endocrinol Metab2011; 25(6): 959–973

[2]

Pickard J, Jochen AL, Sadur CN, Hofeldt FD. Cushing’s syndrome in pregnancy. Obstet Gynecol Surv1990; 45(2): 87–93

[3]

Kamiya Y, Okada M, Yoneyama A, Jin-no Y, Hibino T, Watanabe O, Kajiura S, Suzuki Y, Iwata H, Kobayashi S. Surgical successful treatment of Cushing’s syndrome in a pregnant patient complicated with severe cardiac involvement. Endocr J1998; 45(4): 499–504

[4]

Nakashima YM, Itonaga Y, Inoue H, Takahashi S. Pulmonary edema after laparoscopic adrenalectomy in a pregnant patient with Cushing’s syndrome. J Anesth2000; 14(3): 157–159

[5]

Aishima M, Tanaka M, Haraoka M, Naito S. Retroperitoneal laparoscopic adrenalectomy in a pregnant woman with Cushing’s syndrome. J Urol2000; 164(3 Pt 1): 770–771

[6]

Shaw JA, Pearson DW, Krukowski ZH, Fisher PM, Bevan JS. Cushing’s syndrome during pregnancy: curative adrenalectomy at 31 weeks gestation. Eur J Obstet Gynecol Reprod Biol2002; 105(2): 189–191

[7]

Tejura H, Weiner J, Gibby O, O’Leary AJ, Avasarala S. Cushing’s syndrome in pregnancy. J Obstet Gynaecol2005; 25(7): 713–714

[8]

Sammour RN, Saiegh L, Matter I, Gonen R, Shechner C, Cohen M, Ohel G, Dickstein G. Adrenalectomy for adrenocortical adenoma causing Cushing’s syndrome in pregnancy: a case report and review of literature. Eur J Obstet Gynecol Reprod Biol2012; 165(1): 1–7

[9]

Chang I, Cha HH, Kim JH, Choi SJ, Oh SY, Roh CR. Cushing syndrome in pregnancy secondary to adrenal adenoma. Obstet Gynecol Sci2013; 56(6): 400–403

[10]

Lo KW, Lau TK. Cushing’s syndrome in pregnancy secondary to adrenal adenoma. A case report and literature review. Gynecol Obstet Invest1998; 45(3): 209–212

[11]

Handler J. Cushing’s syndrome with uncontrolled hypertension, occasional hypokalemia, and two pregnancies. J Clin Hypertens (Greenwich)2010; 12(7): 516–521

[12]

Holgado-Galicia MV, Magno JD, Acelajado-Valdenor C, Isip-Tan IT, Lim-Abrahan MA. Cushing’s syndrome in pregnancy. BMJ Case Rep 2011; 2011: bcr0120113720

[13]

Choi WJ, Jung TS, Paik WY. Cushing’s syndrome in pregnancy with a severe maternal complication: a case report. J Obstet Gynaecol Res2011; 37(2): 163–167

[14]

Borna S, Akbari S, Eftekhar T, Mostaan F. Cushing’s syndrome during pregnancy secondary to adrenal adenoma. Acta Med Iran2012; 50(1): 76–78

[15]

Kita M, Sakalidou M, Saratzis A, Ioannis S, Avramidis A. Cushing’s syndrome in pregnancy: report of a case and review of the literature. Hormones (Athens)2007; 6(3): 242–246

[16]

Al Banna R, Husain A, Al Aali J, Ebrahim K, Mohammed. Reversible Cushing dilated cardiomyopathy mimicking peripartum cardiomyopathy with successful subsequent pregnancy. BMJ Case Rep 2011; 2011: bcr0920114825

[17]

Kim HG, Lee KH, Je GH, Han MS. A case of Cushing’s syndrome in pregnancy secondary to an adrenal cortical adenoma. J Korean Med Sci2003; 18(3): 444–446

[18]

Hunt AB, McCONAHEY WM. Pregnancy associated with diseases of the adrenal glands. Am J Obstet Gynecol1953; 66(5): 970–987

[19]

Lindsay JR, Jonklaas J, Oldfield EH, Nieman LK. Cushing’s syndrome during pregnancy: personal experience and review of the literature. J Clin Endocrinol Metab2005; 90(5): 3077–3083

[20]

Vilar L, Freitas MC, Lima LH, Lyra R, Kater CE. Cushing’s syndrome in pregnancy: an overview. Arq Bras Endocrinol Metabol2007; 51(8): 1293–1302

[21]

Cohade C, Broussaud S, Louiset E, Bennet A, Huyghe E, Caron P. Ectopic Cushing’s syndrome due to a pheochromocytoma: a new case in the post-partum and review of literature. Gynecol Endocrinol2009; 25(9): 624–627

[22]

Rask E, Schvarcz E, Hellman P, Hennings J, Karlsson FA, Rao CV. Adrenocorticotropin-independent Cushing’s syndrome in pregnancy related to overexpression of adrenal luteinizing hormone/human chorionic gonadotropin receptors. J Endocrinol Invest2009; 32(4): 313–316

[23]

Terhune KP, Jagasia S, Blevins LS Jr, Phay JE. Diagnostic and therapeutic dilemmas of hypercortisolemia during pregnancy: a case report. Am Surg2009; 75(3): 232–234

[24]

Casonato A, Daidone V, Pontara E, Albiger N, Cattini MG, Scaroni C. Hypercortisolism and pregnancy upregulate von Willebrand factor through different mechanisms: report on a pregnant patient with Cushing’s syndrome. Blood Coagul Fibrinolysis2010; 21(5): 476–479

[25]

Pollack RP, Brett EM. Adrenocorticotropic hormone-independent Cushing syndrome manifesting during pregnancy. Endocr Pract2010; 16(2): 260–263

[26]

Asicioglu E, Gonenli G, Kahveci A, Yildizeli B, Deyneli O, Yavuz D, Yuksel M, Akalin S. Thymic neuroendocrine carcinoma presenting as cushing’s syndrome: treatment with octreotide combined with surgery and radiotherapy. Onkologie2011; 34(1-2): 46–49

[27]

Bednarek-Tupikowska G, Kubicka E, Sicińska-Werner T, Kazimierczak A, Winowski J, Tupikowska M, Janczyszyn M, Bolanowski M. A case of Cushing’s syndrome in pregnancy. Endokrynol Pol2011; 62(2): 181–185

[28]

Boronat M, Marrero D, López-Plasencia Y, Barber M, Schamann Y, Nóvoa FJ. Successful outcome of pregnancy in a patient with Cushing’s disease under treatment with ketoconazole during the first trimester of gestation. Gynecol Endocrinol2011; 27(9): 675–677

[29]

Toutounchi S, Makowska A, Krajewska E, Fiszer P, Cieśla W, Pogorzelski R, Bartnik A, Wielgoś M, Bar-Andziak E, Skórski M. Laparoscopic treatment of Cushing’s syndrome in a woman in late pregnancy- a case presentation. Wideochir Inne Tech Malo Inwazyjne2011; 6(4): 261–263

[30]

Achong N, D’Emden M, Fagermo N, Mortimer R. Pregnancy-induced Cushing’s syndrome in recurrent pregnancies: case report and literature review. Aust N Z J Obstet Gynaecol2012; 52(1): 96–100

[31]

Gopal RA, Acharya SV, Bandgar TR, Menon PS, Shah NS. Cushing disease with pregnancy. Gynecol Endocrinol2012; 28(7): 533–535

[32]

Homer L, Viatge M, Gayet FX, Laurent Y, Kerlan V. Cushing syndrome and pregnancy: a propos of a malignant adrenocortical carcinoma. Gynecol Obstet Fertil2012; 40(3): e1–e4

[33]

Kimura Y, Okuyama K, Mitsui K, Tamaki F, Nonaka A, Matsukawa T. Anesthetic management for laparoscopic adrenalectomy in a pregnant patient with Cushing’s syndrome. Masui2012; 61(6): 605–609

[34]

Garla V, Kheetan R, Saleem T. Cushing’s syndrome in pregnancy: a diagnostic conundrum. W V Med J2013; 109(6): 34–36

[35]

Lim WH, Torpy DJ, Jeffries WS. The medical management of Cushing’s syndrome during pregnancy. Eur J Obstet Gynecol Reprod Biol2013; 168(1): 1–6

[36]

Xu JJ, Wang YJ, Shan LZ, Gu W, Zeng WH. Recurrent ACTH-independent Cushing’s syndrome in multiple pregnancies. Gynecol Endocrinol2013; 29(4): 309–310

[37]

Williams RH, Melmed S. Williams Textbook of Endocrinology. Philadelphia: Elsevier/Saunders, 2011: online resource (1920 p.)

[38]

Lindsay JR, Nieman LK. Adrenal disorders in pregnancy. Endocrinol Metab Clin North Am2006; 35(1): 1–20, v

[39]

Lindsay JR, Nieman LK. The hypothalamic-pituitary-adrenal axis in pregnancy: challenges in disease detection and treatment. Endocr Rev2005; 26(6): 775–799

[40]

Polli N, Pecori Giraldi F, Cavagnini F. Cushing’s syndrome in pregnancy. J Endocrinol Invest2003; 26(10): 1045–1050

RIGHTS & PERMISSIONS

Higher Education Press and Springer-Verlag Berlin Heidelberg

AI Summary AI Mindmap
PDF (89KB)

1594

Accesses

0

Citation

Detail

Sections
Recommended

AI思维导图

/