Esophageal pulse oximetry is more accurate and detects hypoxemia earlier than conventional pulse oximetry during general anesthesia

Abstract

The esophagus is perfused directly by prominent arteries and may provide a more consistent tissue source for pulse oximetry. The goal of this study was to evaluate the sensitivity and accuracy of an esophageal pulse oximetry probe on patients during controlled hypoxemia in comparison to measurements obtained with conventional pulse oximetry (SpulseO₂). Forty-five ASA I–II adult patients were included in this prospective observational study. Nellcor digital oximetric probes were placed on finger tips for SpulseO₂ before anesthesia. After tracheal intubation, an esophageal probe was placed in the lower segment of the esophagus for esophageal oximetric monitoring (SoesO₂). All patients were disconnected from the breathing circuit to establish a controlled hypoxemia, and were re-connected to the breathing circuit and ventilated with 100% oxygen immediately when SoesO₂ dropped to 90%. Matched SoesO₂ and SpulseO₂ readings were recorded when SoesO₂ measurements were at 100%, 95%, 90% and the lowest reading. The time for SoesO₂ and SpulseO₂ to drop from 100% to 95%, 90% and return to 100% was recorded. Oxygen saturation from arterial blood samples (SartO₂) was also measured at each time point respectively. The linear correlation coefficient of the regression analysis between SartO₂ and SoesO₂ was 0.954. The mean±2SD of the difference was 0.3%±4.3% for SoesO₂vs. SartO₂ and 6.8%±5.6% for SpulseO₂vs. SartO₂ (P<0.001). The 95% confidence interval for the absolute difference between SoesO₂ and SartO₂ was 0.3% to 0.7% and 6.2% to 7.4% between SpulseO₂ and SartO₂. The time to reach 90% saturation measured with SoesO₂ was approximately 94 seconds earlier than the SpulseO₂ (P<0.001). In conclusion, SoesO₂ is more accurate and enables earlier detection of hypoxemia when compared to conventional pulse oximetry during hypoxemia for patients undergoing general anesthesia.

Keywords

esophageal pulse oximetry / conventional pulse oximetry / hypoxemia

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Acknowledgements

This study was supported by the Department of Anesthesiology and Translational Neuroscience Center, West China Hospital, Sichuan University and the Laboratory of Statistics, Sichuan University. We would like to thank Shenyi Yang for his support in data collection and analysis and Brenton Scott Alexander and Peixian Gong for their proofreading of the manuscript.

RIGHTS & PERMISSIONS

2014 Higher Education Press and Springer-Verlag Berlin Heidelberg