The second short-term warm ischemia after vascular anastomosis did not affect early renal function recovery in renal transplantation: a case report

Abstract

Ischemic postconditioning was defined as rapid intermittent interruptions of blood flow in the early phase of reperfusion, which has been found to be protective against renal ischemia-reperfusion injury (IRI) in animal models but not in clinical trials. We describe a case that the allograft renal vein was twisted because of the surgeon’s mistake, which caused the warm ischemia of allograft after reperfusion. The allograft restored blood flow without second reperfusion and cold preservation after 9 min of warm ischemia. The patient was followed up for 3 months and the allograft worked well without complications.

Keywords

renal transplantation / vein twist / ischemia-reperfusion injury

References

[1] Ogutmen B, Yildirim A, Sever MS, Bozfakioglu S, Ataman R, Erek E, Cetin O, Emel A. Health-related quality of life after kidney transplantation in comparison intermittent hemodialysis, peritoneal dialysis, and normal controls. Transplant Proc2006; 38(2): 419-421

[2] Hernández D, Rufino M, Armas S, González A, Gutiérrez P, Barbero P, Vivancos S, Rodríguez C, de Vera JR, Torres A. Retrospective analysis of surgical complications following cadaveric kidney transplantation in the modern transplant era. Nephrol Dial Transplant2006; 21(10): 2908-2915

[3] Berlanga JR, Calahorra J, Caramelo C. Acute kidney failure with the absence of renal blood flow during an obstetric catastrophe: renal vasospasm versus cortical necrosis. Nefrologia2004; 24(2): 194-195 (in Spanish) PMID:15219097

[4] Secin FP. Importance and limits of ischemia in renal partial surgery: experimental and clinical research. Adv Urol2008; 2008: 102461

[5] Szwarc I, Soullier S, Gayrard N, Mejean C, Mourad G, Argiles A. Ischemic postconditioning prevents ischemic acute renal failure. Transplant Proc2007; 39(8): 2554-2556

[6] Pagliaro P, Penna C. Cardiac postconditioning. Antioxid Redox Signal2011; 14(5): 777-779

[7] Ovize M, Baxter GF, Di Lisa F, Ferdinandy P, Garcia-Dorado D, Hausenloy DJ, Heusch G, Vinten-Johansen J, Yellon DM, Schulz R. Postconditioning and protection from reperfusion injury: where do we stand? Position paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology. Cardiovasc Res2010; 87(3): 406-423

Acknowledgements

We thank Miss Qian Wang for the help of modifying Fig. 1.

RIGHTS & PERMISSIONS

2014 Higher Education Press and Springer-Verlag Berlin Heidelberg