Interaction and combined toxicity of microplastics and per- and polyfluoroalkyl substances in aquatic environment

Highlights

● Adsorption of PFASs on MPs and its mechanisms are critically reviewed.

● MPs could alter the transport and transformation of PFASs in aquatic environments.

● Combined toxicity of MPs and PFASs at organismal and molecular levels is discussed.

Abstract

Microplastics (MPs) are recognized as vectors for the transport of organic contaminants in aquatic environments in addition to their own adverse effects on aquatic organisms. Per- and polyfluoroalkyl substances (PFASs) are widely present in aquatic environments due to their widespread applications, and thus coexist with MPs. Therefore, we focus on the interaction of MPs and PFASs and related combined toxicity in aquatic environments in this work. The adsorption of PFASs on MPs is critically reviewed, and new mechanisms such as halogen bonding, π-π interaction, cation-π interactions, and micelle formation are proposed. Moreover, the effect of MPs on the transport and transformation of PFASs in aquatic environments is discussed. Based on four typical aquatic organisms (shellfish, Daphnia, algae, and fish), the toxicity of MPs and/or PFASs at the organismal or molecular levels is also evaluated and summarized. Finally, challenges and research perspectives are proposed, and the roles of the shapes and aging process of MPs on PFAS biogeochemical processes and toxicity, especially on PFAS substitutes, are recommended for further investigation. This review provides a better understanding of the interactions and toxic effects of coexisting MPs and PFASs in aquatic environments.

Graphical abstract

Keywords

Microplastics / Per- and Polyfluoroalkyl substances / Adsorption / Transport / Transformation

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Acknowledgements

This research was funded by the National Natural Science Foundation of China (Nos. U2106213, 41907332, and 42192572), the National Postdoctoral Program for Innovative Talents of China (BX20190306), the Taishan Scholars Program of Shandong Province (China) (tsqn201909051), the Fundamental Research Funds for the Central Universities (China) (202141003), and the USDA Hatch Program (USA) (MAS 00549).

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