Effect of gastric fluid on adsorption and desorption of endocrine disrupting chemicals on microplastics

Abstract

• Effect of gastric fluid on EDCs adsorption-desorption to microplastics was evaluated.

• The gastric fluid enhanced desorption of EDCs on the surface of microplastics.

• Adsorption and desorption isotherms fitted the Freundlich model well.

• Desorption ratios of EE2 (55%–59%) on PVC were larger than that of E2 (49%–55%).

• Decrease in pH and increase in ionic strength in gastric fluid strengthen desorption.

Microplastics and endocrine disrupting chemicals are emerging pollutants in the marine environment because of their potential hazards. The effect of gastric fluid on the adsorption and desorption of 17β-estradiol (E2) and 17α-ethynylestradiol (EE2) to microplastics was investigated. The adsorption and desorption isotherms of E2/EE2 on microplastics could be well fitted by the Freundlich model while the Gibbs free energy of these processes were negative, proving that the reaction occurred spontaneously on the heterogeneous surface of the microplastics. Desorption ratios of EE2 (55%–59%) on PVC were larger than that of E2 (49%–55%) to indicate that EE2 was less stable in gastric fluid, which could be explained by the fact that the hydrophobicity of EE2 was greater than E2. E2/EE2 were more easily desorbed from PVC in the gastric fluid and the desorption amount (5.25–12.91/7.19–17.86 μg/g) increased by 2.51 times in comparison with that in saline solution (2.22–7.81/2.87–10.80 μg/g). The decrease of pH and the increase of ionic strength in gastric fluid could further strengthen desorption of E2/EE2 from PVC. The promotion of gastric juice on desorption of PVC was achieved by reducing the hydrophobicity of the PVC surface. The desorption rate of E2/EE2 at 18°C and 38°C was respectively 44%–47%/46%–50% and 49%–55%/56%–59%, indicating that PVC loaded with E2/EE2 had a relatively greater risk of releasing pollutants in the gastric fluid of constant temperature marine organisms while higher temperatures exposed higher hazards for variable temperature animals. The interaction between microplastics and pollutants might be mainly hydrophobic interaction.

Graphical abstract

Keywords

Microplastics / Gastric fluid / Endocrine-disrupting chemicals / Adsorption / Desorption

References

[1] Bakir A, Rowland S J, Thompson R C (2014a). Enhanced desorption of persistent organic pollutants from microplastics under simulated physiological conditions. Environmental pollution, 185: 16–23

[2] Bakir A, Rowland S J, Thompson R C (2014b). Transport of persistent organic pollutants by microplastics in estuarine conditions. Estuarine Coastal and Shelf Science, 140: 14–21

[3] Bao Z Z, Chen Z F, Lu S Q, Wang G, Qi Z, Cai Z (2021). Effects of hydroxyl group content on adsorption and desorption of anthracene and anthrol by polyvinyl chloride microplastics. Science of the Total Environment, 790: 148077

[4] Bucking C, Wood C (2009). The effect of postprandial changes in pH along the gastrointestinal tract on the distribution of ions between the solid and fluid phasesof chyme in rainbow trout. Aquaculture nutrition, 15(3): 282–296

[5] Cai Y, Wu J, Lu J, Wang J, Zhang C (2022). Fate of microplastics in a coastal wastewater treatment plant: Microfibers could partially break through the integrated membrane system. Frontiers of Environmental Science & Engineering, 16(7): 96

[6] Chen Z, Xiao X, Chen B, Zhu L (2015). Quantification of chemical states, dissociation constants and contents of oxygen-containing groups on the surface of biochars produced at different temperatures. Environmental Science & Technology, 49(1): 309–317

[7] Coffin S, Huang G Y, Lee I, Schlenk D (2019). Fish and seabird gut conditions enhance desorption of estrogenic chemicals from commonly-ingested plastic items. Environmental Science & Technology, 53(8): 4588–4599

[8] Deng Y (2020). Low-cost adsorbents for urban stormwater pollution control. Frontiers of Environmental Science & Engineering, 14(5): 83

[9] Du Z, Huang C, Meng J, Yuan Y, Yin Z, Feng L, Liu Y, Zhang L (2020). Sorption of aromatic organophosphate flame retardants on thermally and hydrothermally produced biochars. Frontiers of Environmental Science & Engineering, 14(3): 43

[10] Jambeck J R, Geyer R, Wilcox C, Siegler T R, Perryman M, Andrady A, Narayan R, Law K L (2015). Plastic waste inputs from land into the ocean. Science, 347(6223): 768–771

[11] Khalid N, Aqeel M, Noman A, Hashem M, Mostafa Y S, Alhaithloul H A S, Alghanem S M (2021). Linking effects of microplastics to ecological impacts in marine environments. Chemosphere, 264(Pt 2): 128541

[12] Kurnia K A, Harimurti S, Yung H K, Baraheng A, Sham Alimin M A, Dagang N S M, Fadhilah A, Rosyadi R, Nisa Yahya W Z, Bustam M A (2019). Understanding the effect of pH on the solubility of Gamavuton-0 in the aqueous solution: Experimental and COSMO-RS modeling. Journal of molecular liquids, 296: 111845

[13] Lee H, Lee H J, Kwon J H (2019). Estimating microplastic-bound intake of hydrophobic organic chemicals by fish using measured desorption rates to artificial gut fluid. Science of the Total Environment, 651(Pt 1): 162–170

[14] Li T, Fan Y, Cun D, Dai Y, Liang W (2020). Dibutyl phthalate adsorption characteristics using three common substrates in aqueous solutions. Frontiers of Environmental Science & Engineering, 14(2): 26

[15] Liu W, Cheng F, Li W, Xing B, Tao S (2012). Desorption behaviors of BDE-28 and BDE-47 from natural soils with different organic carbon contents. Environmental pollution, 163: 235–242

[16] Liu X, Wang J (2020). Algae (Raphidocelissubcapitata) mitigate combined toxicity of microplastic and lead on Ceriodaphniadubia. Frontiers of Environmental Science & Engineering, 14(6): 97

[17] Lu J, Lin Y, Wu J, Zhang C (2021b). Continental-scale spatial distribution, sources, and health risks of heavy metals in seafood: Challenge for the water-food-energy nexus sustainability in coastal regions? Environmental Science and Pollution Research International,

[18] Lu J, Wu J, Wang J (2022a). Metagenomic analysis on resistance genes in water and microplastics from a mariculture system. Frontiers of Environmental Science & Engineering, 16(1): 4

[19] Lu J, Wu J, Wu J, Zhang C, Luo Y (2021c). Adsorption and desorption of steroid hormones by microplastics in seawater. Bulletin of Environmental Contamination and Toxicology, 107(4): 730–735.

[20] Lu J, Wu J, Zhang C (2021a). Cleaner production of salt-tolerance vegetable in coastal saline soils using reclaimed water irrigation: Observations from alleviated accumulation of endocrine disrupting chemicals and environmental burden. Journal of Cleaner Production, 297: 126746

[21] Lu J, Wu J, Zhang C, Zhang Y (2020a). Possible effect of submarine groundwater discharge on the pollution of coastal water: Occurrence, source, and risks of endocrine disrupting chemicals in coastal groundwater and adjacent seawater influenced by reclaimed water irrigation. Chemosphere, 250: 126323

[22] Lu J, Zhang C, Wu J (2022b). Removal of steroid hormones from mariculture system using seaweed Caulerpalentillifera. Frontiers of Environmental Science & Engineering, 16(2): 15

[23] Lu J, Zhang Y, Wu J, Wang J, Cai Y (2020b). Fate of antibiotic resistance genes in reclaimed water reuse system with integrated membrane process. Journal of Hazardous Materials, 382: 121025

[24] Mahapatra K, Roy S (2019). An insight into the folding and stability of Arabidopsis thaliana SOG1 transcription factor under salinity stress in vitro. Biochemical and Biophysical Research Communications, 515(4): 531–537

[25] Saini A, Kaur P, Singh K, Bhullar M S (2021). Influence of soil properties, temperature and pH on adsorption-desorption of imazamox on Indian aridisols. Archives of Agronomy and Soil Science: 1–20

[26] Salimova A, Zuo J, Liu F, Wang Y, Wang S, Verichev K (2020). Ammonia and phosphorus removal from agricultural runoff using cash crop waste-derived biochars. Frontiers of Environmental Science & Engineering, 14(3): 48

[27] Spiteri C, Cappellen P V, Regnier P (2008). Surface complexation effects on phosphate adsorption to ferric iron oxyhydroxides along pH and salinity gradients in estuaries and coastal aquifers. Geochimica et Cosmochimica Acta, 72(14): 3431–3445

[28] Stollberg N, Kröger S D, Reininghaus M, Forberger J, Witt G, Brenner M (2021). Uptake and absorption of fluoranthene from spiked microplastics into the digestive gland tissues of blue mussels, Mytilus edulis L. Chemosphere, 279: 130480

[29] Su P., Gao X, Zhang J, Djellabi R, Yang B, Wu Q, Wen Z (2021). Enhancing the adsorption function of biochar by mechanochemical graphitization for organic pollutant removal. Frontiers of Environmental Science & Engineering, 15 (6):130

[30] Tanaka K, Takada H, Yamashita R, Mizukawa K, Fukuwaka M A, Watanuki Y (2015). Facilitated leaching of additive-derived PBDEs from plastic by seabirds’ stomach oil and accumulation in tissues. Environmental Science & Technology, 49(19): 11799–11807

[31] Torres N H, Santos G O S, Romanholo Ferreira L F, Américo-Pinheiro J H P, Eguiluz K I B, Salazar-Banda G R (2021). Environmental aspects of hormones estriol, 17β-estradiol and 17α-ethinylestradiol: Electrochemical processes as next-generation technologies for their removal in water matrices. Chemosphere, 267: 128888

[32] United States Pharmacopeial Convention (1995). Simulated gastric fluid. United States Pharmacopoeia 23/National Formulary 18

[33] Vakili M, Qiu W, Cagnetta G, Huang J, Yu G (2021). Solvent-free mechanochemical mild oxidation method to enhance adsorption properties of chitosan. Frontiers of Environmental Science & Engineering, 15 (6): 128

[34] Velzeboer I, Kwadijk C J A F, Koelmans A A (2014). Strong sorption of PCBs to nanoplastics, microplastics, carbon nanotubes, and fullerenes. Environmental Science & Technology, 48(9): 4869–4876

[35] Wu P, Cai Z, Jin H, Tang Y (2019). Adsorption mechanisms of five bisphenol analogues on PVC microplastics. Science of the Total Environment, 650(Pt 1): 671–678

[36] Zhang C, Lu J, Wu J (2019). Adsorptive removal of polycyclic aromatic hydrocarbons by detritus of green tide algae deposited in coastal sediment. Science of the Total Environment, 670: 320–327

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