Valorization of agro-industrial fruit peel waste to fluorescent nanocarbon sensor: Ultrasensitive detection of potentially hazardous tropane alkaloid

Abstract

• Transformation of agro-industrial waste to value-added material via green chemistry.

• Orange peel is valorized into fluorescent nanodiamond-like carbon (fNDC) sensor.

• fNDC detects potentially hazardous drug atropine sulfate (AS).

• fNDC recognizes AS in biological fluids and pharmaceuticals.

• fNDC assures applications in clinical and forensic toxicology.

Millions of tonnes of agro-industrial waste are generated each year globally, with the vast majority of it going untreated, underutilized, and disposed of by burning or landfilling, causing severe environmental distress and economic downturn. A practical solution to this global issue is to use green chemistry to convert this waste into value-added products. Accordingly, in the present study, agro-industrial orange peel waste was valorized into fluorescent nanodiamond-like carbon sensor via a green route involving hydrothermal treatment of microwave carbonized orange peel waste. The developed sensor, used for the fluorescence detection of potentially hazardous drug atropine sulfate, exhibits unique dual linearity over concentration ranges of 300 nM to 1 M and from 1 M to 10 M, as well as ultra-low sensitivity of 34.42 nM and 356.46 nM, respectively. Additionally, the sensor demonstrates excellent reproducibility, high stability, and satisfactory recovery when used to identify and quantify atropine sulfate in biological samples and commercially available pharmaceuticals, indicating promising multidisciplinary applications.

Graphical abstract

Keywords

Agro-industrial waste / Orange peel / Valorization / Nanodiamond-like carbon / Atropine sulphate / Fluorescence sensing

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