Feasibility assessment of up-flow anaerobic sludge blanket treatment of sulfamethoxazole pharmaceutical wastewater

Abstract

The UASB system successfully treated sulfamethoxazole pharmaceutical wastewater.

High concentration sulfate of this wastewater was the main refractory factor.

UASB recovery performance after a few days of inflow arrest was studied.

The optimal UASB operating conditions for practical application were determined.

Treatment of sulfamethoxazole pharmaceutical wastewater is a big challenge. In this study, a series of anaerobic evaluation tests on pharmaceutical wastewater from different operating units was conducted to evaluate the feasibility of using anaerobic digestion, and the results indicated that the key refractory factor for anaerobic treatment of this wastewater was the high sulfate concentration. A laboratory-scale up-flow anaerobic sludge blanket (UASB) reactor was operated for 195 days to investigate the effects of the influent chemical oxygen demand (COD), organic loading rate (OLR), and COD/SO₄^2‒ ratio on the biodegradation of sulfamethoxazole in pharmaceutical wastewater and the process performance. The electron flow indicated that methanogenesis was still the dominant reaction although sulfidogenesis was enhanced with a stepwise decrease in the influent COD/SO₄^2‒ ratio. For the treated sulfamethoxazole pharmaceutical wastewater, a COD of 4983 mg/L (diluted by 50%), OLR of 2.5 kg COD/(m³·d), and COD/SO₄^2‒ ratio of more than 5 were suitable for practical applications. The recovery performance indicated that the system could resume operation quickly even if production was halted for a few days.

Graphical abstract

Keywords

Up-flow anaerobic sludge blanket (UASB) / Methane production / Sulfate reduction / Sulfamethoxazole pharmaceutical wastewater / Electron flow / Recovery

References

[1] APHA (2005). Standard methods for the examination of water and wastewater. American Water Works Association/American Public Works Association/Water Environment Federation, 21st ed. American Public Health Association, Washington DC, USA

[2] Aydin S, Ince B, Cetecioglu Z, Arikan O, Ozbayram E G, Shahi A, Ince O (2015). Combined effect of erythromycin, tetracycline and sulfamethoxazole on performance of anaerobic sequencing batch reactors. Bioresource Technology, 186(3): 207–214

[3] Cetecioglu Z, Ince B, Gros M, Rodriguez-Mozaz S, Barceló D, Ince O, Orhon D (2015). Biodegradation and reversible inhibitory impact of sulfamethoxazole on the utilization of volatile fatty acids during anaerobic treatment of pharmaceutical industry wastewater. Science of the Total Environment, 536(7): 667–674

[4] Cetecioglu Z, Ince B, Orhon D, Ince O (2016). Anaerobic sulfamethoxazole degradation is driven by homoacetogenesis coupled with hydrogenotrophic methanogenesis. Water Research, 90(12): 79–89

[5] Chen Q Q, Wu W D, Zhang Z Z, Xu J J, Jin R C (2017). Inhibitory effects of sulfamethoxazole on denitrifying granule properties: Short- and long-term tests. Bioresource Technology, 233(2): 391–398

[6] Chen Z, Wang H, Chen Z, Ren N, Wang A, Shi Y, Li X (2011). Performance and model of a full-scale up-flow anaerobic sludge blanket (UASB) to treat the pharmaceutical wastewater containing 6-APA and amoxicillin. Journal of Hazardous Materials, 185(2-3): 905–913

[7] Das B K, Roy S, Dev S, Das D, Bhattacharya J (2015). Improvement of the degradation of sulfate rich wastewater using sweetmeat waste (SMW) as nutrient supplement. Journal of Hazardous Materials, 300(8): 796–807

[8] Hoa T T H, Liamleam W, Annachhatre A P (2007). Lead removal through biological sulfate reduction process. Bioresource Technology, 98(13): 2538–2548

[9] Hu Y, Jing Z, Sudo Y, Niu Q, Du J, Wu J, Li Y Y (2015). Effect of influent COD/SO₄^2‒ratios on UASB treatment of a synthetic sulfate-containing wastewater. Chemosphere, 130(2): 24–33

[10] Isa Z, Grusenmeyer S, Verstraete W (1986). Sulfate reduction relative to methane production in high-rate anaerobic digestion: microbiological aspects. Applied and Environmental Microbiology, 51(3): 580–587

[11] Jeong T Y, Chung H K, Yeom S H, Choi S S (2009). Analysis of methane production inhibition for treatment of sewage sludge containing sulfate using an anaerobic continuous degradation process. Korean Journal of Chemical Engineering, 26(5): 1319–1322

[12] Jia Y, Khanal S K, Zhang H, Chen G H, Lu H (2017). Sulfamethoxazole degradation in anaerobic sulfate-reducing bacteria sludge system. Water Research, 119(4): 12–20

[13] Jing Z, Hu Y, Niu Q, Liu Y, Li Y Y, Wang X C (2013). UASB performance and electron competition between methane-producing archaea and sulfate-reducing bacteria in treating sulfate-rich wastewater containing ethanol and acetate. Bioresource Technology, 137(11): 349–357

[14] Kaksonen A H, Puhakka J A (2007). Sulfate reduction based bioprocesses for the treatment of acid mine drainage and the recovery of metals. Engineering in Life Sciences, 7(6): 541–564

[15] Kiyuna L S M, Fuess L T, Zaiat M (2017). Unraveling the influence of the COD/sulfate ratio on organic matter removal and methane production from the biodigestion of sugarcane vinasse. Bioresource Technology, 232(2): 103–112

[16] Li W, Niu Q, Hong Z, Zhe T, Yu Z, Gao Y, Li Y Y, Nishimura O, Min Y (2015). UASB treatment of chemical synthesis-based pharmaceutical wastewater containing rich organic sulfur compounds and sulfate and associated microbial characteristics. Chemical Engineering Journal, 260(8): 55–63

[17] Li Y, Hu Q, Chen C H, Wang X L, Gao D W (2017). Performance and microbial community structure in an integrated anaerobic fluidized-bed membrane bioreactor treating synthetic benzothiazole contaminated wastewater. Bioresource Technology, 236(3): 1–10

[18] Liu Z H, Maszenan A M, Liu Y, Ng W J (2015). A brief review on possible approaches towards controlling sulfate-reducing bacteria (SRB) in wastewater treatment systems. Desalination and Water Treatment, 53(10): 2799–2807

[19] Lu X, Zhen G, Ni J, Hojo T, Kubota K, Li Y Y (2016). Effect of influent COD/SO₄^2‒ ratios on biodegradation behaviors of starch wastewater in an upflow anaerobic sludge blanket (UASB) reactor. Bioresource Technology, 214(4): 175–183

[20] Mizuno O, Li Y Y, Noike T (1994). Effects of sulfate concentration and sludge retention time on the interaction between methane production and sulfate reduction for butyrate. Water Science and Technology, 30(8): 45–54

[21] Sabumon P C (2008). Development of enhanced sulphidogenesis process for the treatment of wastewater having low COD/SO₄^2‒ ratio. Journal of Hazardous Materials, 159(2-3): 616–625

[22] Shin H S, Oh S E, Lee C Y (1997). Influence of sulfur compounds and heavy metals on the methanization of tannery wastewater. Water Science and Technology, 35(8): 239–245

[23] Sponza D T, Demirden P (2007). Treatability of sulfamerazine in sequential upflow anaerobic sludge blanket reactor (UASB)/completely stirred tank reactor (CSTR) processes. Separation and Purification Technology, 56(1): 108–117

[24] Svojitka J, Dvořák L, Studer M, Straub J O, Frömelt H, Wintgens T (2017). Performance of an anaerobic membrane bioreactor for pharmaceutical wastewater treatment. Bioresource Technology, 229(1): 180–189

[25] Tursman J F, Cork D (1989). Influence of sulfate and sulfate-reducing bacteria on anaerobic digestion technology. Advances in Biotechnological Processes, 12(1): 273–285

[26] Vallero M V G, Lettinga G, Lens P N L (2005). High rate sulfate reduction in a submerged anaerobic membrane bioreactor (SAMBaR) at high salinity. Journal of Membrane Science, 253(1-2): 217–232

[27] Weijma J, Stams A J, Hulshoff Pol L W, Lettinga G (2000). Thermophilic sulfate reduction and methanogenesis with methanol in a high rate anaerobic reactor. Biotechnology and Bioengineering, 67(3): 354–363

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