Research of synthesis and neural network training on double quantum dot colorimetric fluorescent probe for freshness detection

  • Caihong Lv 1,2 ,
  • Yuewei Zheng 1 ,
  • Zhihao Guan 1 ,
  • Jun Qian 2 ,
  • Houbin Li , 2 ,
  • Xinghai Liu , 1
Expand
  • 1. Hubei Engineering Technology Research Center of Spectrum and Imaging Instrument, Electronic Information School, Wuhan University, Wuhan 430072, China
  • 2. School of Nursing, Wuhan University, Wuhan 430072, China
lhb@whu.edu.cn
liuxh@whu.edu.cn

Received date: 22 Mar 2024

Accepted date: 18 Apr 2024

Copyright

2024 Higher Education Press

Abstract

There are many disadvantages such as small detection range and environmental restrictions on application conditions, when the single quantum dot powder or solution is used for fluorescent probe detection. In this paper, the blue fluorescent silicon quantum dots and green fluorescent carbon quantum dots were prepared, and their fluorescence color changes after mixing in different proportions were investigated under different pH conditions. When the two quantum dots were mixed with a concentration of 0.1 mg·mL–1 and a mass ratio of 1:1, the fluorescence color change could be better displayed at a pH from 1 to 14. Meanwhile, the double quantum dots were prepared into two forms (ink and film), successfully realizing the device application of the fluorescent probe. The films and inkjet-printed labels were used to test the spoilage of food (pork, milk, etc.), and the color change data of the labels were collected during the spoilage test. These data were used for neural network training to predict the spoilage changes of foods.

Cite this article

Caihong Lv , Yuewei Zheng , Zhihao Guan , Jun Qian , Houbin Li , Xinghai Liu . Research of synthesis and neural network training on double quantum dot colorimetric fluorescent probe for freshness detection[J]. Frontiers of Chemical Science and Engineering, 2024 , 18(10) : 120 . DOI: 10.1007/s11705-024-2471-8

Competing interests

The authors declare that they have no competing interests.

Acknowledgements

The authors acknowledge the usage of all characterizations supported by the “14th Five-Year Plan” National Key Research and Development Plan Project (Grant No. 2023YFE0105500), and National Natural Science Foundation of China (Grant No. 52173206). The authors also thank the Core Facility of Wuhan University for FTIR, Fluorescence Spectrophotometer, TGA, and TEM.

Electronic Supplementary Material

Supplementary material is available in the online version of this article at https://doi.org/10.1007/s11705-024-2471-8 and is accessible for authorized users.
1
Ghosh T , Sahoo R , Ghosh S K , Banerji P , Das N C . Simplistic hydrothermal synthesis approach for fabricating photoluminescent carbon dots and its potential application as an efficient sensor probe for toxic lead(II) ion detection. Frontiers of Chemical Science and Engineering, 2023, 17(5): 536–547

DOI

2
John B K , Abraham T , Mathew B . A review on characterization techniques for carbon quantum dots and their applications in agrochemical residue detection. Journal of Fluorescence, 2022, 32(2): 449–471

DOI

3
Li N , Zhang Y , Li P , Zhu B , Wang W , Xu Z W . Enhanced permeability and biofouling mitigation of forward osmosis membranes via grafting graphene quantum dots. Frontiers of Chemical Science and Engineering, 2023, 17(10): 1470–1483

DOI

4
Casey J R , Grinstein S , Orlowski J . Sensors and regulators of intracellular pH. Nature Reviews. Molecular Cell Biology, 2010, 11(1): 50–61

DOI

5
Han J , Burgess K . Fluorescent indicators for intracellular pH. Chemical Reviews, 2010, 110(5): 2709–2728

DOI

6
Wang Y , Tang B , Zhang S . A visible colorimetric pH sensitive chemosensor based on azo dye of benzophenone. Dyes and Pigments, 2011, 91(3): 294–297

DOI

7
Snee P T , Somers R C , Nair G , Zimmer J P , Bawendi M G , Nocera D G . A ratiometric CdSe/ZnS nanocrystal pH sensor. Journal of the American Chemical Society, 2006, 128(41): 13320–13321

DOI

8
Zhang X , Li Z , Zhou T , Zhou Q , Zeng Z M , Xu X D , Hu Y G . A quantum dot-spore nanocomposite pH sensor. Talanta, 2016, 150: 184–189

DOI

9
Ji X , Palui G , Avellini T , Na H B , Yi C Y , Knappenberger K L Jr , Mattoussi H . On the pH-dependent quenching of quantum dot photoluminescence by redox active dopamine. Journal of the American Chemical Society, 2012, 134(13): 6006–6017

DOI

10
Deb A , Konwar A , Chowdhury D . pH-responsive hybrid jute carbon dot-cotton patch. ACS Sustainable Chemistry & Engineering, 2020, 8(19): 7394–7402

DOI

11
Miao X , Qu D , Yang D , Nie B , Zhao Y K , Fan H Y , Sun Z C . Synthesis of carbon dots with multiple color emission by controlled graphitization and surface functionalization. Advanced Materials, 2018, 30(1): 1704740

DOI

12
Dang H , Huang L , Zhang Y , Wang C F , Chen S . Large-scale ultrasonic fabrication of white fluorescent carbon dots. Industrial & Engineering Chemistry Research, 2016, 55(18): 5335–5341

DOI

13
Vallan L , Urriolabeitia E P , Ruiperez F , Matxain J M , Canton-Vitoria R , Tagmatarchis N , Benito A M , Maser W K . Supramolecular-enhanced charge transfer within entangled polyamide chains as the origin of the universal blue fluorescence of polymer carbon dots. Journal of the American Chemical Society, 2018, 140(40): 12862–12869

DOI

14
Wu X , Zhao B , Zhang J , Xu H , Xu K Q , Chen G . Photoluminescence and photodetecting properties of the hydrothermally synthesized nitrogen-doped carbon quantum dots. Journal of Physical Chemistry C, 2019, 123(42): 25570–25578

DOI

15
Zhu Y , Yao Y , Chen Z , Zhang Z T , Zhang P , Cheng Z F , Gao Y F . WO3 quantum dot photochromical film. Solar Energy Materials and Solar Cells, 2022, 239: 111664

DOI

16
Valais I , Michail C , Fountzoula C , Tseles D , Yannakopoulos P , Nikolopoulos D , Bakas A , Fountos G , Saatsakis G , Sianoudis I . . On the response of alloyed ZnCdSeS quantum dot films. Results in Physics, 2017, 7: 1734–1736

DOI

17
Wang Y , Shang M , Wang Y , Cui B W , Qiu Z J , Li H , Wang Y X . Polyimide composite films reinforced by graphene quantum dots. Fullerenes, Nanotubes, and Carbon Nanostructures, 2022, 30(6): 683–691

DOI

18
Wang T , Zhou C , Zhang X , Xu D . Waterborne polyurethanes prepared from benzophenone derivatives with delayed fluorescence and room-temperature phosphorescence. Polymer Chemistry, 2018, 9(11): 1303–1308

DOI

19
Xi T , Tang L , Hao W , Yao L L , Cui P . Morphology and pervaporation performance of ionic liquid and waterborne polyurethane composite membranes. RSC Advances, 2018, 8(14): 7792–7799

DOI

20
Han T , Lam J W , Zhao N , Gao M , Yang Z Y , Zhao E G , Dong Y P , Tang B Z . A fluorescence-switchable luminogen in the solid state: a sensitive and selective sensor for the fast “turn-on” detection of primary amine gas. Chemical Communications, 2013, 49(42): 4848–4850

DOI

21
FuX. Preparation of silicon quantum dots its application in anti-counterfeiting. Wuhan University, 2019

22
Tang A , Liu Y , Wang Q , Chen R S , Liu W Y , Fang Z Q , Wang L S . A new photoelectric ink based on nanocellulose/CdS quantum dots for screen-printing. Carbohydrate Polymers, 2016, 148: 29–35

DOI

23
Sliz R , Lejay M , Fan J Z , Choi M J , Kinge S , Hoogland S , Fabritius T , De Arguer F P G , Sargent E H . Stable colloidal quantum dot inks enable inkjet-printed high-sensitivity infrared photodetectors. ACS Nano, 2019, 13(10): 11988–11995

DOI

24
Hou X , Chen G , Xing T , Wei Z Z . Reactive ink formulated with various alcohols for improved properties and printing quality onto cotton fabrics. Journal of Engineered Fibers and Fabrics, 2019, 14: 1925957988

DOI

25
Tawiah B , Howard E K , Asinyo B K . The chemistry of inkjet inks for digital textile printing—review. International Journal of Management. Information Technology and Engineering, 2016, 4(5): 61–78

26
Ghosh T , Nandi S , Bhattacharyya S K , Ghosh S K , Mandal M , Banerji P , Das N C . Nitrogen and sulphur doped carbon dot: an excellent biocompatible candidate for in-vitro cancer cell imaging and beyond. Environmental Research, 2023, 217: 114922

DOI

27
Ghosh T , Das T K , Das P , Banerji P , Das N C . Current scenario and recent advancement of doped carbon dots: a short review scientocracy update (2013–2022). Carbon Letter, 2022, 32(4): 953–977

DOI

28
Atchudan R , Edison T N J I , Perumal S , Vinodh R , Lee Y R . Betel-derived nitrogen-doped multicolor carbon dots for environmental and biological applications. Journal of Molecular Liquids, 2019, 296: 111817–111817

DOI

29
Atchudan R , Edison T N J I , Perumal S , Muthuchamy N , Lee Y R . Hydrophilic nitrogen-doped carbon dots from biowaste using dwarf banana peel for environmental and biological applications. Fuel, 2020, 275: 117821

DOI

30
Atchudan R , Kishore S C , Gangadaran P , Edison T N J I , Perumal S , Rajendran R L , Alagan M , Al-Rashed S , Ahn B C , Lee Y R . Tunable fluorescent carbon dots from biowaste as fluorescence ink and imaging human normal and cancer cells. Environmental Research, 2022, 204: 112365

DOI

31
Fang S , Guan Z , Su C , Zhang W S , Zhu J , Zheng Y W , Li H B , Zhao P P , Liu X H . Accurate fish-freshness prediction label based on red cabbage anthocyanins. Food Control, 2022, 138: 109018

DOI

32
Guo L , Wang T , Wu Z , Wang J W , Wang M , Cui Z Q , Ji S B , Cai J F , Xu C L , Chen X D . Portable food‐freshness prediction platform based on colorimetric barcode combinatorics and deep convolutional neural networks. Advanced Materials, 2020, 32(45): 2004805

DOI

33
Dager A , Uchida T , Maekawa T , Tachibana M . Synthesis and characterization of mono-disperse carbon quantum dots from fennel seeds: photoluminescence analysis using machine learning. Scientific Reports, 2019, 9(1): 14004

DOI

34
Atchudan R , Gangadaran P , Edison T N J I , Perumal S , Sundramoorthy A K , Vinodh R , Rajendran R L , Ahn B C , Lee Y R . Betel leaf derived multicolor emitting carbon dots as a fluorescent probe for imaging mouse normal fibroblast and human thyroid cancer cells. Physica E, Low-Dimensional Systems and Nanostructures, 2022, 136: 115010

DOI

35
Fu X , Li G , Cai S , Yang H , Lin K , He M , Wen J W , Li H B , Xiong Y B , Chen D Z . . Color-switchable hybrid dots/hydroxyethyl cellulose ink for anti-counterfeiting applications. Carbohydrate Polymers, 2021, 251: 117084

DOI

36
Jiang K , Sun S , Zhang L , Lu Y , Wu A G , Cai C Z , Lin H W . Red, green, and blue luminescence by carbon dots: full-color emission tuning and multicolor cellular imaging. Angewandte Chemie International Edition, 2015, 54(18): 5360–5363

DOI

37
Yang X , Pan Z T , Ma Y . Rhoda mine B as standard substance to measure the fluorescence-quantum yield of dichlorofluorescein. Journal of Analytical Sciences, 2003, 19(6): 588–589

38
Li C , You H , Zhang Z , Dai Z Q , Guan J T , Wei B M . Synthesis and optoelectronic properties of an arylamine-endcapped spirofluorene for blue light emission. Organic Chemistry, 2011, 31(12): 2095–2101 (in Chinese)

39
Velapoldi R A , Tnnesen H H . Corrected emission spectra and quantum yields for a series of fluorescent compounds in the visible spectral region. Journal of Fluorescence, 2004, 14(4): 465–472

DOI

40
Zheng Y , Li X , Huang Y , Li H B , Chen L Y , Liu X H . Two colorimetric films based on chitin whiskers and sodium alginate/gelatin incorporated with anthocyanins for monitoring food freshness. Food Hydrocolloids, 2022, 127: 107517

DOI

41
Dissing B S , Papadopoulou O S , Tassou C , Ersboll B K , Carstensen J M , Panagou E Z , Nychas G J . Using multispectral imaging for spoilage detection of pork meat. Food and Bioprocess Technology, 2013, 6(9): 2268–2279

DOI

42
Ullah R , Khan S , Ali H , Bilal M . Potentiality of using front face fluorescence spectroscopy for quantitative analysis of cow milk adulteration in buffalo milk. Spectrochimica Acta. Part A: Molecular and Biomolecular Spectroscopy, 2020, 225: 117518

DOI

43
Waligorski P , Szaleniec M . Prediction of white cabbage (Brassica oleracea var. capitata) self-incompatibility based on neural network and discriminant analysis of complex electrophoretic patterns. Computational Biology and Chemistry, 2010, 34(2): 115–121

DOI

44
Chumachenko K , Iosifidis A , Gabbouj M . Feedforward neural networks initialization based on discriminant learning. Neural Networks, 2022, 146: 220–229

DOI

45
Xiao X , Cao S , Wang L , Cheng S L , Yuan E R . Deep hashing image retrieval based on hybrid neural network and optimized metric learning. Knowledge-Based Systems, 2024, 284: 111336

DOI

46
Rawat W , Wang Z . Deep convolutional neural networks for image classification: a comprehensive review. Neural Computation, 2017, 29(9): 2352–2449

DOI

47
Zhang X , Chen C , Peng D , Zhou Y Z , Zhuang J L , Zhang X J , Lei B F , Liu Y L , Hu C F . pH-responsive carbon dots with red emission for real-time and visual detection of amines. Journal of Materials Chemistry. C, Materials for Optical and Electronic Devices, 2020, 8(33): 11563–11571

DOI

48
Somaraj G , Mathew S , Abraham T , Ambady K G , Mohan C , Mathew B . Nitrogen and sulfur co-doped carbon quantum dots for sensing applications: a review. ChemistrySelect, 2022, 7(19): e202200473

DOI

49
Khan A , Ezati P , Rhim J W , Kim J T , Molaei R . pH-sensitive green tea-derived carbon quantum dots for real-time monitoring of shrimp freshness. Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 2023, 666: 131242

DOI

50
Guo Z , Luo J , Zhu Z , Sun Z S , Zhang X G , Wu Z C , Mo F W , Guan A X . A facile synthesis of high-efficient N,S co-doped carbon dots for temperature sensing application. Dyes and Pigments, 2020, 173: 107952

DOI

51
Tang M M , Chen C , Song J Z , Ni Y B , Xiang B , Zou J , Xu D K . Safety of plant fiber-based food contact materials: overview of the discovery, identification, detection and risk assessment of unknown risk substances. Food Packaging and Shelf Life, 2024, 43: 101281

DOI

52
Kumar J V , Rhim J W . Fluorescent carbon quantum dots for food contaminants detection applications. Journal of Environmental Chemical Engineering, 2024, 12(2): 111999

DOI

Outlines

/