Frontiers of Chemical Science and Engineering >
Iron oxide nanoparticle-based theranostics for cancer imaging and therapy
Received date: 30 Mar 2014
Accepted date: 15 Apr 2014
Published date: 11 Oct 2014
Copyright
Theranostic platform, which is equipped with both diagnostic and therapeutic functions, is a promising approach in cancer treatment. From various nanotheranostics studied, iron oxide nanoparticles have advantages since IONPs have good biocompatibility and spatial imaging capability. This review is focused on the IONP-based nanotheranostics for cancer imaging and treatment. The most recent progress for applications of IONP nanotheranostics is summarized, which includes IONP-based diagnosis, magnetic resonance imaging (MRI), multimodal imaging, chemotherapy, hyperthermal therapy, photodynamic therapy, and gene delivery. Future perspectives and challenges are also outlined for the potential development of IONP based theranostics in clinical use.
Xiaoqing REN , Hongwei CHEN , Victor YANG , Duxin SUN . Iron oxide nanoparticle-based theranostics for cancer imaging and therapy[J]. Frontiers of Chemical Science and Engineering, 2014 , 8(3) : 253 -264 . DOI: 10.1007/s11705-014-1425-y
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