Glyco-functionalised quantum dots and their progress in cancer diagnosis and treatment

Jayshree Ashree, Qi Wang, Yimin Chao

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Front. Chem. Sci. Eng. ›› 2020, Vol. 14 ›› Issue (3) : 365-377. DOI: 10.1007/s11705-019-1863-7
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Glyco-functionalised quantum dots and their progress in cancer diagnosis and treatment

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Abstract

Despite all major breakthroughs in recent years of research, we are still unsuccessful to effectively diagnose and treat cancer that has express and metastasizes. Thus, the development of a novel approach for cancer detection and treatment is crucial. Recent progress in Glyconanotechnology has allowed the use of glycans and lectins as bio-functional molecules for many biological and biomedical applications. With the known advantages of quantum dots (QDs) and versatility of carbohydrates and lectins, Glyco-functionalised QD is a new prospect in constructing biomedical imaging platform for cancer behaviour study as well as treatment. In this review, we aim to describe the current utilisation of Glyco-functionalised QDs as well as their future prospective to interpret and confront cancer.

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Keywords

carbohydrate / leptin / glyco-functionalised QD / bioimaging / cancer diagnosis and treatment

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Jayshree Ashree, Qi Wang, Yimin Chao. Glyco-functionalised quantum dots and their progress in cancer diagnosis and treatment. Front. Chem. Sci. Eng., 2020, 14(3): 365‒377 https://doi.org/10.1007/s11705-019-1863-7

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This research received no external funding. The authors declare no conflict of interest.

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