Sodium cellulose sulfate: A promising biomaterial used for microcarriers’ designing

Abstract

Due to a worldwide focus on sustainable materials for human health and economy services, more and more natural renewable biomass are regarded as promising materials that could replace synthetic polymers and reduce global dependence on petroleum resources. Cellulose is known as the most abundant renewable polymer in nature, varieties of cellulose-based products have been developed and have gained growing interest in recent years. In this review, a kind of water-soluble cellulose derivative, i.e., sodium cellulose sulfate (NaCS) is introduced. Details about NaCS’s physicochemical properties like solubility, biocompatibility, biodegradability, degree of substitution, etc. are systematically elaborated. And promising applications of NaCS used as biomaterials for microcarriers’ designing, such as micro-cell-carriers, micro-drug-carriers, etc., are presented.

Graphical abstract

Keywords

sodium cellulose sulfate / biomaterial / physicochemical properties / microcarriers

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Acknowledgments

This work was funded by China Postdoctoral Science Foundation (No. 2017M611998), the National Natural Science Foundation of China (Grant Nos. 21606002 and 21576233), the Natural Science Foundation of Anhui Province (CN) (No. 1708085QC64), the Doctoral Research Start-up Fund of Anhui University (J01001319), and the Undergraduate Research Training Programs for Innovation (Nos. KYXL2017036, 201710357034 and 201710357268).

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