This article presents our experiences in hepatic resection of 467 cases over a period of 22 years with a total operative mortality of 4.0%. Of the 467 cases, malignancies were found in 288 cases, benign lesions in 179 cases; extensive hemihepatectomy was done in 194 cases, and lobectomy or partial resection in 273 cases. Follow-up results: The cases of non-malignant tumors are living well. In cases of metastatic liver cancer, the mean survival time was 1.4 years. The 5-year survival rate of primary liver cancer was 24.8%, while that of the malignant tumors sized less than 5 cm in diameter amounted to 53.8%. In this paper, the authors focussed the discussion on the selection of patients, judgment of the resectability of tumor during operation, improvements in operative technic and the prevention and treatment of surgical complications.

In the present study 40 mature rabbits were used to cause de-arrangement of the articular surfaces by arthrotomy. The ultrastructural changes of the articular cartilage in the pathological model were studied under transmission electron microscope and scanning electron microscope. The striking changes observed were pycnosis of chondrocytes, calcification of cartilage matrix and rupture of the arched structure of collagen fibre. However, increase of rough surfaced endoplasmic reticulum in some chondrocytes and rupture of arched structure of collagen fibre were not ever described in previous literature. Using the experimental model, we attempt to analyse the principle of degeneration of articular cartilage caused by articular mechanical changes, and consequently suggest the proper clinical treatment for osteoarthrosis and osteoarthritic injury.

The ACh content and turnover in the brain of rat during the course of acupuncture analgesia (AA) were investigated. In electro-acupuncture (EA) group, the pain threshold was significantly higher than that of the control (P<0.0l) and the acetylcholine (ACh) content in the brain increased obviously.

In order to determine the rate of ACh utilization and synthesis, hemicholineum-3 (HC-3) and physostigmine were used as tool drugs to block the synthesis and degradation of ACh respectively. It was discovered that during AA, the ACh utilization rate increased significantly in comparison with the control group. In caudate nucleus it increased to more than twice and in thalamus nearly to twice the amount. At the same time the rate of ACh synthesis also increased. These indicate that the elevation of ACh content in the central nerve system (CNS) is the result of a new dynamic equilibrium between the increase in ACh utilization rate and synthesis rate induced by EA. Reviewing a lot of papers concerned, one can see that the increase in ACh utilization rate is an important evidence that ACh actively participates in the action of AA.

With a self-designed peritoneo-venous shunt device, the authors made experimental studies in 10 dogs and 1 monkey which were rendered ascitic by constriction of the vena cava just above the diaphragm. Ascites disappeared in all animals rapidly following insertion of shunt device. From Nov. 1980 to Jan. 1983, this peritoneo-venous shunt device was applied clinically in 24 patients with intractable ascites, among whom 12 developed the disease due to schistosomiasis and 12 were late cases of liver cirrhosis. Ascites disappeared in all cases in 3–14 days with decrease of the abdominal circumference and improvement of the patients’ general condition.