Numerical method for axial motion artifact correction in retinal spectral-domain optical coherence tomography
Sergey Yu. KSENOFONTOV, Pavel A. SHILYAGIN, Dmitry A. TERPELOV, Valentin M. GELIKONOV, Grigory V. GELIKONOV
Numerical method for axial motion artifact correction in retinal spectral-domain optical coherence tomography
A numerical method that compensates image distortions caused by random fluctuations of the distance to an object in spectral-domain optical coherence tomography (SD OCT) has been proposed and verified experimentally. The proposed method is based on the analysis of the phase shifts between adjacent scans that are caused by micrometer-scale displacements and the subsequent compensation for the displacements through phase-frequency correction in the spectral space. The efficiency of the method is demonstrated in model experiments with harmonic and random movements of a scattering object as well as during in vivo imaging of the retina of the human eye.
optical coherence tomography (OCT) / motion artifact correction / retinal imaging / numerical method
[1] |
Fercher A F, Hitzenberger C K, Kamp G, El-Zaiat S Y. Measurement of intraocular distances by backscattering spectral interferometry. Optics Communications, 1995, 117(1–2): 43–48
CrossRef
Google scholar
|
[2] |
Gelikonov V M, Gelikonov G V, Terpelov D A, Shilyagin P A. Electronic interface systems for goals of spectral domain optical coherence tomography. Instruments and Experimental Techniques, 2012, 55(3): 392–398
CrossRef
Google scholar
|
[3] |
Rajabi H, Zirak A. Speckle noise reduction and motion artifact correction based on modified statistical parameters estimation in OCT images. Biomedical Physics & Engineering Express, 2016, 2(3): e035012
CrossRef
Google scholar
|
[4] |
Kang W, Wang H, Wang Z, Jenkins M W, Isenberg G A, Chak A, Rollins A M. Motion artifacts associated with in vivo endoscopic OCT images of the esophagus. Optics Express, 2011, 19(21): 20722–20735
CrossRef
Pubmed
Google scholar
|
[5] |
de Kinkelder R, Kalkman J, Faber D J, Schraa O, Kok P H B, Verbraak F D, van Leeuwen T G. Heartbeat-induced axial motion artifacts in optical coherence tomography measurements of the retina. Investigative Ophthalmology & Visual Science, 2011, 52(6): 3908–3913
CrossRef
Pubmed
Google scholar
|
[6] |
Zawadzki R J, Miller D T. Retinal AO OCT. In: Drexler W, Fujimoto J G, eds. Optical Coherence Tomography: Technology and Applications. 2nd ed. Switzerland: Springer International Publishing, 2015, 1849–1920
|
[7] |
Gelikonov V M, Gelikonov G V, Shilyagin P A. Optimization of Fizeau-based optical coherence tomography with a reference michelson interferometer. Bulletin of the Russian Academy of Sciences. Physics, 2008, 72(1): 93–97
|
[8] |
Kraus M F, Potsaid B, Mayer M A, Bock R, Baumann B, Liu J J, Hornegger J, Fujimoto J G. Motion correction in optical coherence tomography volumes on a per A-scan basis using orthogonal scan patterns. Biomedical Optics Express, 2012, 3(6): 1182–1199
CrossRef
Pubmed
Google scholar
|
[9] |
Kraus M F, Liu J J, Schottenhamml J, Chen C L, Budai A, Branchini L, Ko T, Ishikawa H, Wollstein G, Schuman J, Duker J S, Fujimoto J G, Hornegger J. Quantitative 3D-OCT motion correction with tilt and illumination correction, robust similarity measure and regularization. Biomedical Optics Express, 2014, 5(8): 2591–2613
CrossRef
Pubmed
Google scholar
|
[10] |
Chen Z, Shen Y, Bao W, Li P, Wang X, Ding Z. Motion correction using overlapped data correlation based on a spatial-spectral encoded parallel optical coherence tomography. Optics Express, 2017, 25(6): 7069–7083
CrossRef
Pubmed
Google scholar
|
[11] |
Chen Y, Hong Y J, Makita S, Yasuno Y. Eye-motion-corrected optical coherence tomography angiography using Lissajous scanning. Biomedical Optics Express, 2018, 9(3): 1111–1129
CrossRef
Pubmed
Google scholar
|
[12] |
Potsaid B, Gorczynska I, Srinivasan V J, Chen Y, Jiang J, Cable A, Fujimoto J G. Ultrahigh speed spectral/Fourier domain OCT ophthalmic imaging at 70000 to 312500 axial scans per second. Optics Express, 2008, 16(19): 15149–15169
CrossRef
Pubmed
Google scholar
|
[13] |
Lezama J, Mukherjee D, McNabb R P, Sapiro G, Kuo A N, Farsiu S. Segmentation guided registration of wide field-of-view retinal optical coherence tomography volumes. Biomedical Optics Express, 2016, 7(12): 4827–4846
CrossRef
Pubmed
Google scholar
|
[14] |
Camino A, Zhang M, Dongye C, Pechauer A D, Hwang T S, Bailey S T, Lujan B, Wilson D J, Huang D, Jia Y. Automated registration and enhanced processing of clinical optical coherence tomography angiography. Quantitative Imaging in Medicine and Surgery, 2016, 6(4): 391–401
CrossRef
Pubmed
Google scholar
|
[15] |
Baghaie A, Yu Z, D’Souza R M. Involuntary eye motion correction in retinal optical coherence tomography: hardware or software solution? Medical Image Analysis, 2017, 37: 129–145
CrossRef
Pubmed
Google scholar
|
[16] |
Camino A, Zhang M, Gao S S, Hwang T S, Sharma U, Wilson D J, Huang D, Jia Y. Evaluation of artifact reduction in optical coherence tomography angiography with real-time tracking and motion correction technology. Biomedical Optics Express, 2016, 7(10): 3905–3915
CrossRef
Pubmed
Google scholar
|
[17] |
Lang A, Carass A, Al-Louzi O, Bhargava P, Solomon S D, Calabresi P A, Prince J L. Combined registration and motion correction of longitudinal retinal OCT data. In: Proceedings of SPIE, Volume 9784, Medical Imaging 2016: Image Processing. San Diego: SPIE, 2016, 97840X
CrossRef
Pubmed
Google scholar
|
[18] |
Watanabe Y, Takahashi Y, Numazawa H. Graphics processing unit accelerated intensity-based optical coherence tomography angiography using differential frames with real-time motion correction. Journal of Biomedical Optics, 2013, 19(2): 021105
CrossRef
Pubmed
Google scholar
|
[19] |
Shemonski N D, Ahn S S, Liu Y Z, South F A, Carney P S, Boppart S A. Three-dimensional motion correction using speckle and phase for in vivo computed optical interferometric tomography. Biomedical Optics Express, 2014, 5(12): 4131–4143
CrossRef
Pubmed
Google scholar
|
[20] |
Lee J, Srinivasan V, Radhakrishnan H, Boas D A. Motion correction for phase-resolved dynamic optical coherence tomography imaging of rodent cerebral cortex. Optics Express, 2011, 19(22): 21258–21270
CrossRef
Pubmed
Google scholar
|
[21] |
Carrasco-Zevallos O M, Nankivil D, Viehland C, Keller B, Izatt J A. Pupil tracking for real-time motion corrected anterior segment optical coherence tomography. PLoS One, 2016, 11(8): e0162015
CrossRef
Pubmed
Google scholar
|
[22] |
Braaf B, Vienola K V, Sheehy C K, Yang Q, Vermeer K A, Tiruveedhula P, Arathorn D W, Roorda A, de Boer J F. Real-time eye motion correction in phase-resolved OCT angiography with tracking SLO. Biomedical Optics Express, 2013, 4(1): 51–65
CrossRef
Pubmed
Google scholar
|
[23] |
Montuoro A, Wu J, Waldstein S, Gerendas B, Langs G, Simader C, Schmidt-Erfurth U. Motion artefact correction in retinal optical coherence tomography using local symmetry. In: Proceedings of MICCAI International Conference on Medical Image Computing and Computer-Assisted Intervention. Boston: Springer, 2014, 17, 130–137
|
[24] |
Hu Z, Rollins A M. Fourier domain optical coherence tomography with a linear-in-wavenumber spectrometer. Optics Letters, 2007, 32(24): 3525–3527
CrossRef
Pubmed
Google scholar
|
[25] |
Gelikonov V M, Gelikonov G V, Shilyagin P A. Linear-wavenumber spectrometer for high-speed spectral-domain optical coherence tomography. Optics and Spectroscopy, 2009, 106(3): 459–465
CrossRef
Google scholar
|
[26] |
Shilyagin P A, Ksenofontov S Y, Moiseev A A, Terpelov D A, Matkivsky V A, Kasatkina I V, Mamaev Y A, Gelikonov G V, Gelikonov V M. Equidistant recording of the spectral components in ultra-wideband spectral-domain optical coherence tomography. Radiophysics and Quantum Electronics, 2018, 60(10): 769–778
CrossRef
Google scholar
|
[27] |
Terpelov D A, Ksenofontov S Y, Gelikonov G V, Gelikonov V M, Shilyagin P A. A data-acquisition and control system for spectral-domain optical coherence tomography with a speed of 91 912 A-scans/s based on a USB 3.0 interface. Instruments and Experimental Techniques, 2017, 60(6): 868–874
CrossRef
Google scholar
|
[28] |
Leitgeb R A, Wojtkowski M. Complex and coherence-noise free Fourier domain optical coherence tomography. In: Drexler W, Fujimoto J G, eds. Optical Coherence Tomography: Technology and applications. 2nd ed. Switzerland: Springer International Publishing, 2015, 195–224
|
[29] |
Gelikonov V M, Gelikonov G V, Kasatkina I V, Terpelov D A, Shilyagin P A. Coherent noise compensation in spectral-domain optical coherence tomography. Optics and Spectroscopy, 2009, 106(6): 895–900
CrossRef
Google scholar
|
[30] |
Ai J, Wang L V. Synchronous self-elimination of autocorrelation interference in Fourier-domain optical coherence tomography. Optics Letters, 2005, 30(21): 2939–2941
CrossRef
Pubmed
Google scholar
|
[31] |
Leitgeb R A, Hitzenberger C K, Fercher A F, Bajraszewski T. Phase-shifting algorithm to achieve high-speed long-depth-range probing by frequency-domain optical coherence tomography. Optics Letters, 2003, 28(22): 2201–2203
CrossRef
Pubmed
Google scholar
|
[32] |
Zhang J, Nelson J S, Chen Z. Removal of a mirror image and enhancement of the signal-to-noise ratio in Fourier-domain optical coherence tomography using an electro-optic phase modulator. Optics Letters, 2005, 30(2): 147–149
CrossRef
Pubmed
Google scholar
|
[33] |
Matkivsky V A, Moiseev A A, Ksenofontov S Y, Kasatkina I V, Gelikonov G V, Shabanov D V, Shilyagin P A, Gelikonov V M. Medium chromatic dispersion calculation and correction in spectral-domain optical coherence tomography. Frontiers of Optoelectronics, 2017, 10(3): 323–328
CrossRef
Google scholar
|
[34] |
Gelikonov G V, Gelikonov V M. Measurement and compensation for the amplitude and phase spectral distortions of an interference signal in optical coherence tomography for the relative optical-spectrum width exceeding 10%. Radiophysics and Quantum Electronics, 2018, 61(2): 135–145
CrossRef
Google scholar
|
[35] |
Matveev L A, Zaitsev V Y, Gelikonov G V, Matveyev A L, Moiseev A A, Ksenofontov S Y, Gelikonov V M, Sirotkina M A, Gladkova N D, Demidov V, Vitkin A. Hybrid M-mode-like OCT imaging of three-dimensional microvasculature in vivo using reference-free processing of complex valued B-scans. Optics Letters, 2015, 40(7): 1472–1475
CrossRef
Pubmed
Google scholar
|
[36] |
Moiseev A, Ksenofontov S, Sirotkina M, Kiseleva E, Gorozhantseva M, Shakhova N, Matveev L, Zaitsev V, Matveyev A, Zagaynova E, Gelikonov V, Gladkova N, Vitkin A, Gelikonov G. Optical coherence tomography-based angiography device with real-time angiography B-scans visualization and hand-held probe for everyday clinical use. Journal of Biophotonics, 2018, 11(10): e201700292
CrossRef
Pubmed
Google scholar
|
[37] |
Huo L, Xi J, Wu Y, Li X. Forward-viewing resonant fiber-optic scanning endoscope of appropriate scanning speed for 3D OCT imaging. Optics Express, 2010, 18(14): 14375–14384
CrossRef
Pubmed
Google scholar
|
[38] |
Moon S, Lee S W, Rubinstein M, Wong B J F, Chen Z. Semi-resonant operation of a fiber-cantilever piezotube scanner for stable optical coherence tomography endoscope imaging. Optics Express, 2010, 18(20): 21183–21197
CrossRef
Pubmed
Google scholar
|
[39] |
Park H C, Seo Y H, Jeong K H. Lissajous fiber scanning for forward viewing optical endomicroscopy using asymmetric stiffness modulation. Optics Express, 2014, 22(5): 5818–5825
CrossRef
Pubmed
Google scholar
|
[40] |
Chen Y, Hong Y J, Makita S, Yasuno Y. Three-dimensional eye motion correction by Lissajous scan optical coherence tomography. Biomedical Optics Express, 2017, 8(3): 1783–1802
CrossRef
Pubmed
Google scholar
|
[41] |
Chauhan B C, Stevens K T, Levesque J M, Nuschke A C, Sharpe G P, O’Leary N, Archibald M L, Wang X. Longitudinal in vivo imaging of retinal ganglion cells and retinal thickness changes following optic nerve injury in mice. PLoS One, 2012, 7(6): e40352
CrossRef
Pubmed
Google scholar
|
[42] |
Taibbi G, Peterson G C, Syed M F, Vizzeri G. Effect of motion artifacts and scan circle displacements on Cirrus HD-OCT retinal nerve fiber layer thickness measurements. Investigative Ophthalmology & Visual Science, 2014, 55(4): 2251–2258
CrossRef
Pubmed
Google scholar
|
[43] |
Bezerra H G, Costa M A, Guagliumi G, Rollins A M, Simon D I. Intracoronary optical coherence tomography: a comprehensive review clinical and research applications. JACC: Cardiovascular Interventions, 2009, 2(11): 1035–1046
Pubmed
|
[44] |
Ksenofontov S, Vasilenkova T. Method of optimizing maximum intensity projection technique for rendering scalar three-dimensional data in static mode, in interactive mode and in real time. Patent of Russian Federation RU 2533055, 2014
|
[45] |
Ksenofontov S Y. Application of the method of multiple mutual synchronization of parallel computational threads in spectral-domain optical coherent tomography systems. Instruments and Experimental Techniques, 2019, 62(3): 317–323
CrossRef
Google scholar
|
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