封面图片
2019年, 第6卷 第1期
SALL4 belongs to the spalt family which contains several alternative splicing variants that are differentially expressed and are vital for maintaining pluripotent stem cells. However, the molecular features and function of SALL4 have not been adequately elucidated in porcine induced pluripotent stem cells (piPSCs). Since SALL4 and other pluripotent factors were reported to be relevant to embryo development and pluripotent stem cells self-renewal, we investigated the expressions of OCT4 and SOX2 in undifferentiated piPSCs. Immunofluorescence staining revealed high levels of expression of pluripotent factors OCT4 and SOX2 in piPSCs, but the expression of these factors was not evident in differentiated cells.
(Ning WANG, Sile WANG, Yaxian WANG, Yuanxing CAI, Fan YANG, Huayan WANG, pp. 81-92)[展开] ...