Bayesian Inference via GeTex-OTS Based Stochastic Synapse for Uncertainty-Aware Medical Diagnostics
Xinyu Wen , Lun Wang , Kuan Wang , Vivian Zhao , Zixuan Liu , Kexun He , Jianguo Yang , Hao Tong , Xiangshui Miao , Yuhui He
SmartMat ›› 2026, Vol. 7 ›› Issue (1) : e70062
Neuromorphic architectures leveraging stochastic device physics present a transformative approach for implementing probabilistic computing paradigms capable of intrinsic uncertainty quantification. In this work, we present a germanium-telluride-based ovonic threshold switch (GeTex-OTS) exhibiting inherent stochastic dynamics, integrated into a compact 1-selector-1-transistor-1-resistor (1S1T1R) synaptic unit. The OTS devices are demonstrated within an 8K-array, confirming the future scalability for neuromorphic systems. Experimental validation on the GeTex devices shows stable Gaussian-distributed threshold voltage fluctuations (σ = 100 mV), enabling precise control of synaptic activation probability through input pulse modulation. Utilizing this intrinsic stochasticity, we implement mini hardware realization of a Monte Carlo Dropconnect (MC-Dropconnect) neural network, directly demonstrating the feasibility of the system. Applied to COVID-19 diagnosis using chest X-ray images, our system achieves robust uncertainty quantification through predictive entropy, improving classification accuracy to 98.1%, compared to 96.0% with a deterministic baseline. This uncertainty-aware hardware design strategy provides a scalable pathway for implementing energy-efficient neuromorphic systems with native uncertainty estimation capabilities.
Monte Carlo dropconnect / ovonic threshold switch / probabilistic computing / stochastic synapse / uncertainty-aware
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2026 The Author(s). SmartMat published by Tianjin University and John Wiley & Sons Australia, Ltd.
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