Innovation and development of stent retrievers in acute ischemic stroke

Nan Zhang , Hongye Xu , Hongjian Zhang , Hongyu Ma , Weilong Hua , Minghao Song , Yongxin Zhang , Jianmin Liu , Lei Zhang , Xiaoxi Zhang , Pengfei Yang

Front. Med. ›› 2025, Vol. 19 ›› Issue (5) : 789 -806.

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Front. Med. ›› 2025, Vol. 19 ›› Issue (5) : 789 -806. DOI: 10.1007/s11684-025-1160-4
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Innovation and development of stent retrievers in acute ischemic stroke

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Abstract

Acute ischemic stroke (AIS) is a cerebrovascular disease characterized by high morbidity, disability, and mortality, posing a significant threat to human health. Endovascular treatment has now been established as a key method for AIS management, in which stent retrievers that can mechanically remove blood clots play a key role in this technique. In recent years, stent retrievers have evolved in complexity and functionality to improve the ability of clot removing and surgical safety. However, the present instruments still have limitations on treatment efficiency, vascular adaptability, and operational precision, posing an urgent need for innovation in the design of stent retrievers. This paper systematically reviewed the structural features and working principles of AIS stent retrievers from the perspective of efficacy evaluation metrics, historical development, recent advancements in stent retrieval technology, and future prospects.

Keywords

stent retrievers / acute ischemic stroke / innovation / outlook

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Nan Zhang, Hongye Xu, Hongjian Zhang, Hongyu Ma, Weilong Hua, Minghao Song, Yongxin Zhang, Jianmin Liu, Lei Zhang, Xiaoxi Zhang, Pengfei Yang. Innovation and development of stent retrievers in acute ischemic stroke. Front. Med., 2025, 19(5): 789-806 DOI:10.1007/s11684-025-1160-4

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