Betaine: an exercise mimetics for healthy aging?

References

[1] Pedersen BK. The physiology of optimizing health with a focus on exercise as medicine. Annu Rev Physiol 2019; 81(1): 607–627

[2] Paffenbarger RS Jr, Hyde RT, Wing AL, Hsieh CC. Physical activity, all-cause mortality, and longevity of college alumni. N Engl J Med 1986; 314(10): 605–613

[3] Pedersen BK, Saltin B. Exercise as medicine—evidence for prescribing exercise as therapy in 26 different chronic diseases. Scand J Med Sci Sports 2015; 25(Suppl 3): 1–72

[4] GengLPingJWuRYanTZhangHZhuangYNingTWangJLiangC. Systematic profiling reveals betaine as an exercise mimetic for geroprotection. Cell 2025; [Epub ahead of print] doi: 10.1016/j.cell.2025.06.001

[5] Hargreaves M, Spriet LL. Exercise metabolism: fuels for the fire. Cold Spring Harb Perspect Med 2018; 8: a029744

[6] Luo J, Yang H, Song BL. Mechanisms and regulation of cholesterol homeostasis. Nat Rev Mol Cell Biol 2020; 21(4): 225–245

[7] Jang AY, Lim S, Jo SH, Han SH, Koh KK. New trends in dyslipidemia treatment. Circ J 2021; 85(6): 759–768

RIGHTS & PERMISSIONS

Higher Education Press