Preliminary clinical study on non-transecting anastomotic bulbomembranous urethroplasty

Abstract

This study aims to investigate the effect of non-transecting anastomotic urethroplasty for treatment of posterior urethral stricture. A total of 23 patients with traumatic posterior urethral stricture were enrolled and then divided into two groups. In one group, 12 patients underwent non-transecting anastomotic urethroplasty. In the other group, 11 patients underwent conventional posterior urethra end-to-end anastomosis. The effect of operation was evaluated using the following parameters: the bleeding amount during operation, operation time, IIEF-5 scores after operation, maximum flow rate (Qmax), and rating scale of quality of life (QoL). The comparison between the conventional posterior urethra end-to-end anastomosis group and the non-transecting anastomotic urethroplasty group showed no significant difference with regard to average operation time. However, a significant difference was observed between the groups with regard to the bleeding amount during operation. The patients in the group of non-transecting anastomotic urethroplasty urinated smoothly after the removal of catheter. Meanwhile, one patient from the group of conventional posterior urethra end-to-end anastomosis had difficulty urinating after the removal of catheter. Furthermore, significant differences in the operation time, bleeding amount during operation, IIEF-5 scores after operation, and rating scale of QoL were observed, whereas no significant difference was observed between urine flow rates of the two groups after operation. Overall, non-transecting anastomotic urethroplasty is effective for posterior urethra reconstruction, and it can reduce the occurrence rate of erectile dysfunction after operation.

Keywords

anastomotic urethroplasty / transecting / posterior urethra reconstruction

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Acknowledgements

This work was supported by the National Natural Science Foundation of China (No.81370793). We are very grateful to Prof. Yuemin Xu for his guidance in the design of this study, the operation part, and the provision of some patients’ follow-up data.

Compliance with ethics guidelines

Wei Le, Chao Li, Jinfu Zhang, Denglong Wu, and Bo Liu declare that they have no conflict of interest. The study was approved by the ethics committee of Tongji Hospital Affiliated to Tongji University (No. 2012-19-1J).

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