E-waste environmental contamination and harm to public health in China

Abstract

The adverse effects of electronic waste (e-waste) on the human body have stirred up concern in recent years. China is one of the countries that confront serious pollution and human exposure of e-waste, and the majority of the population is exposed to potentially hazardous substances that are derived from informal e-waste recycling processes. This study reviews recent reports on human exposure to e-waste in China, with particular focus on exposure routes (e.g., inhalation and ingestion) and several toxicities of human (e.g., endocrine system, respiratory system, reproductive system, developmental toxicity, neurotoxicity, and genetic toxicity). Pieces of evidence that associate e-waste exposure with human health effects in China are assessed. The role of toxic heavy metals (e.g., lead, cadmium, chromium, mercury, and nickel) and organic pollutants (e.g., polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyl (PCBs), polycyclic aromatic hydrocarbons (PAHs), polybrominated biphenyls (PBBs), polyhalogenated aromatic hydrocarbons (PHAHs), bisphenol A (BPA)) on human health is also briefly discussed.

Keywords

e-waste / heavy metal / organic pollutant / hazardous / toxicity / human health / China

References

[1] Chen A, Dietrich KN, Huo X, Ho SM. Developmental neurotoxicants in e-waste: an emerging health concern. Environ Health Perspect2011; 119(4): 431-438

[2] Hicks C, Dietmar R, Eugster M. The recycling and disposal of electrical and electronic waste in China—legislative and market responses. Environ Impact Assess Rev2005; 25(5): 459-471

[3] Chen M. Investigation on end-of-life electric and electronic equipment recycling and disposal system in China: legislation, education and dissemination. J Cent South Univ Technol2005; 12(2): 148-152

[4] Huo X, Peng L, Xu X, Zheng L, Qiu B, Qi Z, Zhang B, Han D, Piao Z. Elevated blood lead levels of children in Guiyu, an electronic waste recycling town in China. Environ Health Perspect2007; 115(7): 1113-1117

[5] Realff MJ, Raymond M, Ammons JC. E-waste: an opportunity. Mater Today 2004; 7(1): 40-45

[6] Leung AO, Duzgoren-Aydin NS, Cheung KC, Wong MH. Heavy metals concentrations of surface dust from e-waste recycling and its human health implications in southeast China. Environ Sci Technol2008; 42(7): 2674-2680

[7] Guo Y, Huang C, Zhang H, Dong Q. Heavy metal contamination from electronic waste recycling at Guiyu, Southeastern China. J Environ Qual2009; 38(4): 1617-1626

[8] Han W, Feng J, Gu Z, Chen D, Wu M, Fu J. Polybrominated diphenyl ethers in the atmosphere of Taizhou, a major e-waste dismantling area in China. Bull Environ Contam Toxicol2009; 83(6): 783-788

[9] Tang X, Shen C, Shi D, Cheema SA, Khan MI, Zhang C, Chen Y. Heavy metal and persistent organic compound contamination in soil from Wenling: an emerging e-waste recycling city in Taizhou area, China. J Hazard Mater2010; 173(1-3): 653-660

[10] Zheng L, Wu K, Li Y, Qi Z, Han D, Zhang B, Gu C, Chen G, Liu J, Chen S, Xu X, Huo X. Blood lead and cadmium levels and relevant factors among children from an e-waste recycling town in China. Environ Res2008; 108(1): 15-20

[11] Liu J, Xu X, Wu K, Piao Z, Huang J, Guo Y, Li W, Zhang Y, Chen A, Huo X. Association between lead exposure from electronic waste recycling and child temperament alterations. Neurotoxicology2011; 32(4): 458-464

[12] Li Y, Xu X, Liu J, Wu K, Gu C, Shao G, Chen S, Chen G, Huo X. The hazard of chromium exposure to neonates in Guiyu of China. Sci Total Environ2008; 403(1-3): 99-104

[13] Li Y, Huo X, Liu J, Peng L, Li W, Xu X. Assessment of cadmium exposure for neonates in Guiyu, an electronic waste pollution site of China. Environ Monit Assess2011; 177(1-4): 343-351

[14] Bi X, Thomas GO, Jones KC, Qu W, Sheng G, Martin FL, Fu J. Exposure of electronics dismantling workers to polybrominated diphenyl ethers, polychlorinated biphenyls, and organochlorine pesticides in South China. Environ Sci Technol2007; 41(16): 5647-5653

[15] Ren G, Yu Z, Ma S, Li H, Peng P, Sheng G, Fu J. Determination of Dechlorane Plus in serum from electronics dismantling workers in South China. Environ Sci Technol2009; 43(24): 9453-9457

[16] Zhao G, Wang Z, Zhou H, Zhao Q. Burdens of PBBs, PBDEs, and PCBs in tissues of the cancer patients in the e-waste disassembly sites in Zhejiang, China. Sci Total Environ2009; 407(17): 4831-4837

[17] Zahir F, Rizwi SJ, Haq SK, Khan RH. Low dose mercury toxicity and human health. Environ Toxicol Pharmacol2005; 20(2): 351-360

[18] Marinković N, Pašalić D, Ferenčak G, Gršković B, Stavljenić Rukavina A. Dioxins and human toxicity. Arh Hig Rada Toksikol2010; 61(4): 445-453

[19] Ju Y, Xu G, Chen L, Shi J. Effects of the electronic waste pollution on the levels of thyroid hormone and its receptor expression in the parturient woman and the newborn. J Hyg Res (Wei Sheng Yan Jiu)2008; 37(5): 536-539 (in Chinese)

[20] Yuan J, Chen L, Chen D, Guo H, Bi X, Ju Y, Jiang P, Shi J, Yu Z, Yang J, Li L, Jiang Q, Sheng G, Fu J, Wu T, Chen X. Elevated serum polybrominated diphenyl ethers and thyroid-stimulating hormone associated with lymphocytic micronuclei in Chinese workers from an E-waste dismantling site. Environ Sci Technol2008; 42(6): 2195-2200

[21] Zhang J, Jiang Y, Zhou J, Wu B, Liang Y, Peng Z, Fang D, Liu B, Huang H, He C, Wang C, Lu F. Elevated body burdens of PBDEs, dioxins, and PCBs on thyroid hormone homeostasis at an electronic waste recycling site in China. Environ Sci Technol2010; 44(10): 3956-3962

[22] Wang H, Zhang Y, Liu Q, Wang F, Nie J, Qian Y. Examining the relationship between brominated flame retardants (BFR) exposure and changes of thyroid hormone levels around e-waste dismantling sites. Int J Hyg Environ Health2010; 213(5): 369-380

[23] Bi X, Thomas GO, Jones KC, Qu W, Sheng G, Martin FL, Fu J. Exposure of electronics dismantling workers to polybrominated diphenyl ethers, polychlorinated biphenyls, and organochlorine pesticides in South China. Environ Sci Technol2007; 41(16): 5647-5653

[24] Han G, Ding G, Lou X, Wang X, Han J, Shen H, Zhou Y, Du L. Correlations of PCBs, DIOXIN, and PBDE with TSH in children’s blood in areas of computer E-waste recycling. Biomed Environ Sci2011; 24(2): 112-116

[25] Yang Y, Lu XS, Li DL, Yu YJ. Effects of environmental lead pollution on blood lead and sex hormone levels among occupationally exposed group in an E-waste dismantling area. Biomed Environ Sci2013; 26(6): 474-484

[26] Zhou X, Ju Y, Wu Z, Yang K. Disruption of sex hormones and oxidative homeostasis in parturient women and their matching fetuses at an e-waste recycling site in China. Int J Occup Environ Health2013; 19(1): 22-28

[27] Crouch E, Wright JR. Surfactant proteins a and d and pulmonary host defense. Annu Rev Physiol2001; 63(1): 521-554

[28] Zheng G, Xu X, Li B, Wu K, Yekeen TA, Huo X. Association between lung function in school children and exposure to three transition metals from an e-waste recycling area. J Expo Sci Environ Epidemiol2013; 23(1): 67-72

[29] Xu X, Yang H, Chen A, Zhou Y, Wu K, Liu J, Zhang Y, Huo X. Birth outcomes related to informal e-waste recycling in Guiyu, China. Reprod Toxicol2012; 33(1): 94-98

[30] Guo Y, Huo X, Wu K, Liu J, Zhang Y, Xu X. Carcinogenic polycyclic aromatic hydrocarbons in umbilical cord blood of human neonates from Guiyu, China. Sci Total Environ2012; 427-428: 35-40

[31] Wu K, Xu X, Liu J, Guo Y, Li Y, Huo X. Polybrominated diphenyl ethers in umbilical cord blood and relevant factors in neonates from Guiyu, China. Environ Sci Technol2010; 44(2): 813-819

[32] Wu K, Xu X, Liu J, Guo Y, Huo X. In utero exposure to polychlorinated biphenyls and reduced neonatal physiological development from Guiyu, China. Ecotoxicol Environ Saf2011; 74(8): 2141-2147

[33] Wu K, Xu X, Peng L, Liu J, Guo Y, Huo X. Association between maternal exposure to perfluorooctanoic acid (PFOA) from electronic waste recycling and neonatal health outcomes. Environ Int2012; 48: 1-8

[34] Xu X, Yekeen TA, Xiao Q, Wang Y, Lu F, Huo X. Placental IGF-1 and IGFBP-3 expression correlate with umbilical cord blood PAH and PBDE levels from prenatal exposure to electronic waste. Environ Pollut2013; 182: 63-69

[35] Yang H, Huo X, Yekeen TA, Zheng Q, Zheng M, Xu X. Effects of lead and cadmium exposure from electronic waste on child physical growth. Environ Sci Pollut Res Int2013; 20(7): 4441-4447

[36] Xu X, Yekeen TA, Liu J, Zhuang B, Li W, Huo X. Chromium exposure among children from an electronic waste recycling town of China. Environ Sci Pollut Res Int2015; 22(3): 1778-1785

[37] Sieratowicz A, Stange D, Schulte-Oehlmann U, Oehlmann J. Reproductive toxicity of bisphenol A and cadmium in Potamopyrgus antipodarum and modulation of bisphenol A effects by different test temperature. Environ Pollut2011; 159(10): 2766-2774

[38] Xu X, Zhang Y, Yekeen TA, Li Y, Zhuang B, Huo X. Increase male genital diseases morbidity linked to informal electronic waste recycling in Guiyu, China. Environ Sci Pollut Res Int2014; 21(5): 3540-3545

[39] Wang X, Miller G, Ding G, Lou X, Cai D, Chen Z, Meng J, Tang J, Chu C, Mo Z, Han J. Health risk assessment of lead for children in tinfoil manufacturing and e-waste recycling areas of Zhejiang Province, China. Sci Total Environ2012; 426: 106-112

[40] Li Y, Xu X, Wu K, Chen G, Liu J, Chen S, Gu C, Zhang B, Zheng L, Zheng M, Huo X. Monitoring of lead load and its effect on neonatal behavioral neurological assessment scores in Guiyu, an electronic waste recycling town in China. J Environ Monit2008; 10(10): 1233-1238

[41] Halliwell B, Whiteman M. Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean? Br J Pharmacol2004; 142(2): 231-255

[42] Li R, Yang Q, Qiu X, Li K, Li G, Zhu P, Zhu T. Reactive oxygen species alteration of immune cells in local residents at an electronic waste recycling site in northern China. Environ Sci Technol2013; 47(7): 3344-3352

[43] Liu Q, Cao J, Li KQ, Miao XH, Li G, Fan FY, Zhao YC. Chromosomal aberrations and DNA damage in human populations exposed to the processing of electronics waste. Environ Sci Pollut Res Int2009; 16(3): 329-338

[44] Huo X, Peng L, Qiu B, Zheng L, Yekeen TA, Xu X. ALAD genotypes and blood lead levels of neonates and children from e-waste exposure in Guiyu, China. Environ Sci Pollut Res Int2014; 21(10): 6744-6750

[45] Lin S, Huo X, Zhang Q, Fan X, Du L, Xu X, Qiu S, Zhang Y, Wang Y, Gu J. Short placental telomere was associated with cadmium pollution in an electronic waste recycling town in China. PLoS ONE2013; 8(4): e60815

[46] Li Y, Li M, Liu Y, Song G, Liu N. A microarray for microRNA profiling in spermatozoa from adult men living in an environmentally polluted site. Bull Environ Contam Toxicol2012; 89(6): 1111-1114

[47] Zhang Q, Zhou T, Xu X, Guo Y, Zhao Z, Zhu M, Li W, Yi D, Huo X. Downregulation of placental S100P is associated with cadmium exposure in Guiyu, an e-waste recycling town in China. Sci Total Environ2011; 410-411: 53-58

[48] Kurenova EV, Mason JM. Telomere functions. A review. Biochemistry (Mosc)1997; 62(11): 1242-1253

[49] Akkad A, Hastings R, Konje JC, Bell SC, Thurston H, Williams B. Telomere length in small-for-gestational-age babies. BJOG2006; 113(3): 318-323

[50] Biron-Shental T, Sukenik-Halevy R, Sharon Y, Goldberg-Bittman L, Kidron D, Fejgin MD, Amiel A. Short telomeres may play a role in placental dysfunction in preeclampsia and intrauterine growth restriction. Am J Obstet Gynecol2010; 202(4): 381.e1-7

[51] Broberg K, Björk J, Paulsson K, Höglund M, Albin M. Constitutional short telomeres are strong genetic susceptibility markers for bladder cancer. Carcinogenesis2005; 26(7): 1263-1271

[52] Shen J, Terry MB, Gurvich I, Liao Y, Senie RT, Santella RM. Short telomere length and breast cancer risk: a study in sister sets. Cancer Res2007; 67(11): 5538-5544

[53] Hastie ND, Dempster M, Dunlop MG, Thompson AM, Green DK, Allshire RC. Telomere reduction in human colorectal carcinoma and with ageing. Nature1990; 346(6287): 866-868

[54] Blasco MA. Telomeres and human disease: ageing, cancer and beyond. Nat Rev Genet2005; 6(8): 611-622

[55] Liu Q, Cao J, Li KQ, Miao XH, Li G, Fan FY, Zhao YC. Chromosomal aberrations and DNA damage in human populations exposed to the processing of electronics waste. Environ Sci Pollut Res Int2009; 16(3): 329-338

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