On the basis of our experience with 200 cases undergoing free toe transfer for reconstruction of the thumb and fingers, circulatory crisis during and after operation has been analysed in this paper with our classification according to the time of occurrence. In circulatory crisis during operation or within 24 h postoperatively early exploration is indicated. Crises occurring 24, especially 48 h after operation are mainly due to vascular spasm, therefore antispasmodic therapy should be instituted whereas surgical intervention is useless and even harmful.

The infrared spectroscope, polarizing microscope and scanning electron microscope were used in the study of the composition and structure of urinary calculi. It was found that most calculi contained calcium oxalate, but none of them was pure. The nuclei of calcium oxalate-uric acid microcrystal type of calculi only consisted of pure uric acid without any matrix or other elements, indicating that the nuclei are probably formed first by precipitation, crystallization and aggregation of uric acid, and then deposition of calcium oxalate is induced. Foreign bodies in calcium oxalate calculi were mostly necrotic tissues with a large amount of apatites, which is most probably due to bacterial infection of the urinary tract.

Growth pattern in vitro and karyotype of cultured bone marrow cells were studied in 31 patients with acute nonlymphocytic leukemia. Two different growth patterns were identified: cluster growth (pattern I), and no growth (pattern ll). Patients with growth pattern I had a significantly higher complete remission (CR) rate clinically than those with growth pattern I. A serial study of 23 patients during induction treatment showed three different patterns: (1) colony growth, (2) persistence of clusters, and (3) persistence of no growth. The prognosis of the patients with the first pattern was most favourable, 11 of 13 patients achieved CR on an average of 24 days after first detection of colony formation. The data from 152 cultures showed that the colony forming ability had a negative correlation with the percentage of marrow blasts. Karyotype analysis with G-banding technique was successfully performed in 26 patients, in 14 of whom abnormal clones were detected. There was no difference in CR rates between groups NN, A A and AN, although CR was more easily achieved in patients with t(8; 2l). No relationship was seen between growth pattern and karyotype.