Effect of Pasta ulmi on malaria parasites

Abstract

The extract of Pasta ulmi was examined in vivo and in vitro for antimalaria effect. During animal experiments lipophil extract appeared to have a stronger effect than whole extract, whereas the water diluted extract had no therapeutic effect. In the cell culture the isolated fraction of lipophil extract C₁, C₂ and C₄ showed no inhibitory effect on P. falciparum, but the fraction C₀ and C₃ with a concentration of 10 μg/ml medium demonstrated a totally parasiticical effect on parasites on the 5th day of culture.

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