Study onin vivo release of levonorgestrel-containing silicon capsule

Abstract

Thein vivo release rate of levonorgestrel-containing silicon capsule (in vitro releasing rate: 6 μg/d) placed in rabbits was determined. The results showed that the average release per year was 8. 32 μg withr being 0. 96000. The release pattern of the levonorgestrel-containing silicon capsule system was proved to be zero-order release. Our study provided some experimental data for clinical use of the system for birth control.

Keywords

levonorgestrel / releasing system / in vivo release rate / medicated IUD

References

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