The diagnosis value and its implication of impulse oscillometry in obstructive sleep apnea syndrome patients

Abstract

The change of measurements of impulse oscillometry (IOS) in obstructive sleep apnea syndrome (OSAS) patients and its mechanism were observed. The respiratory impedance was measured by using IOS technique and polysomnography (PSG) was monitored synchronously in 36 OSAS patients, 14 patients with chronic obstructive pulmonary disease (COPD) and 12 normal controls. Results showed that R₂₀ in OSAS group was significantly higher than in COPD group and control group (P < 0. 01). R₅-R₂₀ in OSAS group was lower than that in COPD group, but significantly higher than that in control group (P< 0. 01). The levels of R₂₀ and R₅-R₂₀ were positively correlated with severity degree of the disease. In addition, apnea-hyponea index (AHI) was positively correlated with R₅ and R₂₀ with the correlation index (r)being 0. 66 and 0. 86 respectively. The lowest SO₂ was negatively correlated with R₅ and R₅-R₂₀, with r being -0. 66 and -0. 79 respectively. The mean SO₂ was negatively correlated with R₅ and R₅-R₂₀ with r being -0. 81 and -0. 69 respectively. IOS technique could be used as a valuable tool for assessing the degree of upper airway obstruction in the patients with OSAS, and could help to explore its pathological mechanism.

Keywords

obstructive sleep apnea syndrome / impulse oscillometry / airway impedance

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