Studies on the antifertility components from Marsdenia koi

Yuan Jin-Ian , Ding Wei-pei , Shi Jian-ping , Lu Zhi-zhen , Zhou Bing-nan , Clemens A. J. Erdelmeier , Geoffrey A. Cordell , Harry H. S. Fong , Normann R. Farnsworth

Current Medical Science ›› 1991, Vol. 11 ›› Issue (3) : 165 -168.

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Current Medical Science ›› 1991, Vol. 11 ›› Issue (3) : 165 -168. DOI: 10.1007/BF02888129
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Studies on the antifertility components from Marsdenia koi

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Abstract

By random screening test, Marsdenia koi was found to have antifertility activity on SD rat. From MeOH extracts of this plant two steroidal glycosides, marsdekoiside A and B, were isolated, and their structures were elucidated on the basis of spectral evidence and by comparison of the hydrolysis products with the authentic samples. Both are newly identified compounds, and marsdekoiside A has good antifertility activity.

Keywords

Marsdenia koi / marsdekoiside A / marsdekoiside B / steroidal glycoside / antifertility

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Yuan Jin-Ian, Ding Wei-pei, Shi Jian-ping, Lu Zhi-zhen, Zhou Bing-nan, Clemens A. J. Erdelmeier, Geoffrey A. Cordell, Harry H. S. Fong, Normann R. Farnsworth. Studies on the antifertility components from Marsdenia koi. Current Medical Science, 1991, 11(3): 165-168 DOI:10.1007/BF02888129

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