Studies on the maximum permissible concentration of tetrachlorvinphos in surface water

Abstract

By a series of toxicological experiments, including studies on chronic toxicity, teratogenesis and reproduction, Ames’ assay and carcinogenic observation, the non-effective level of tetrachlorvinphos (TCVP) was determined to be 0.15 mg/kg wt. Based on this, the acceptable daily intake for an adult was calculated to be 0.9 mg, including 9% (i.e. 0.081 mg) from drinking water. If an adult takes 3 liters of water per day, the concentration of TCVP in water should be 0.027 mg/1, approximately 0.03 mg/1. Both the requirements of the effects of TCVP on the organoleptic characteristics and self-purification processes in surface water can also be satisfied with 0.03 mg/1. Thus, the authors suggest that the maximum permissible concentration of TCVP in surface water could be established as 0.03 mg/1.

Keywords

tetrachlorvinphos / maximum permissible concentration

References

[1] (1): 66, 1978

[2] 9(2): 7, 1980

[3] AmesBN, et al. . Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test. Mut Res, 1975, 31347-347

[4] CernaM, et al. . Mutagenicity of nitrofurylacrylic acid for Salmonella typhimurium. Mut Res, 1980, 771-1

[5] National Cancer Institute (USA): Bioassay of tetrachlorovinphos for possible carcinogenicity, NCI-CG-TR-33, 1978

[6] 1974

[7] 1979

[8] Красовский ГН: Санита рнаqj охрqaqnqa водоyeмов от за грязнения промыщле-н ымqi сточными водамqi, Вы пуск 5 стр 384, Медгиз, Моси ва, 1962

[9] WalkerAIT, et al. . Toxicological studies with the insecticide tetrachlorvinphos. Pestic Sci, 1972, 3517-517

[10] Спыну ЕИ и др. Комплен сное гиги-енческоye нор мированqiye нсвых Фос-Фо рорганических пести цидов в объек-тах внещ ней срyeqdqy. Гqiг Сан, 1972, 1196