Editors: Michael Q. Zhang and Xuegong Zhang
The year 2021 is the 20th anniversary of the publication of the draft human genome. The sequencing of the human genome has brought life sciences into a new era, the era to understand the information systems of life in a quantitative manner. Today, Quantitative Biology is proud to publish a series of featured articles to celebrate the anniversary. They are from leading scientists who have played major roles and made significant contributions in the Human Genome Project or have evidenced its major progresses and influences. We believe such a collection will not only help to uncover the stories behind the revolutionary project, but will bring many insights that will shed light on the future development of quantitative biology.
Editors: Luhua Lai, Shao Li
Systems biology approaches provide new perspectives in pharmacological sciences, especially Traditional Chinese Medicine (TCM). In recent years, exciting progress has been witnessed in applying systems biology to the field of TCM study. This Collection aims to highlight the advances and perspectives of systems biology in TCM.Luhua
Lai
As huge amounts of omics data are being accumulated in biological fields, more and more studies are becoming data-driven. Mathematical and statistical models, bioinformatics methods, algorithms and analysis pipelines are becoming crucial in all these fields. However, most publications focus on scientific results. It is often challenging for readers to fully understand and replicate published methods, algorithms or pipelines, due to insufficient description on them in the original papers and their supplementary materials. This collection is launched to guide readers to utilize the protocols and tutorials that were not described in detail in other published scientific studies.
After sequencing
the genomes of many species, more and more evidences show that the
configuration of genome in 3D is vital for gene regulation. Through interacting
with nuclear architecture, the organization of the 3D genome regulates cell
differentiation and development. This collection is launched to share the
recent research about 3D genome from Quantitative
Biology.