Mathematical approaches in studying bicoid gene

Abstract

It is widely believed that in Drosophila melanogaster the pattern of Bicoid protein gradient plays a crucial role in the segmentation stage of embryo development. As a result of its fundamental role, modelling the Bicoid gradient has become increasingly popular for researchers from many different areas of study. The aim of this paper is to bring together the most prominent studies on this maternal gene and discuss how existing techniques for modelling this gradient have evolved over the years.

Graphical abstract

Keywords

bicoid / Drosophila melanogaster / model / segmentation gene

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COMPLIANCE WITH ETHICS GUIDELINES

The authors Hossein Hassani, Zara Ghodsi and Kevin McGhee declare that they have no conflict of interests.

This article does not contain any studies with human or animal subjects performed by any of the authors.

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2015 Higher Education Press and Springer-Verlag Berlin Heidelberg