Downregulation of RhoA/ROCK1/YAP/F-actin causing decreased aortic smooth muscle cell stiffness promotes aortic dissection formation

Wei Zhang; Mengxiao Wang; Enci Wang; Wei Lu; Zengxia Li; Yuchong Zhang; Gaofei Hu; Qi Zhang; Wenxin Shan; Yongjun Dang; Zhe Zhao; Lemin Zheng; Weiguo Fu; Lixin Wang

doi:10.1093/lifemeta/loae022

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Life Metabolism ›› 2024, Vol. 3 ›› Issue (5) : loae022. DOI: 10.1093/lifemeta/loae022

Letter

Downregulation of RhoA/ROCK1/YAP/F-actin causing decreased aortic smooth muscle cell stiffness promotes aortic dissection formation

Wei Zhang¹^,² ,
Mengxiao Wang³ ,
Enci Wang¹^,² ,
Wei Lu⁴ ,
Zengxia Li⁵ ,
Yuchong Zhang¹^,² ,
Gaofei Hu³ ,
Qi Zhang³ ,
Wenxin Shan³ ,
Yongjun Dang⁵ ,
Zhe Zhao⁶ ,
Lemin Zheng³ ,
Weiguo Fu¹^,²^,⁶ ,
Lixin Wang¹^,²^,⁷

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Wei Zhang, Mengxiao Wang, Enci Wang, Wei Lu, Zengxia Li, Yuchong Zhang, Gaofei Hu, Qi Zhang, Wenxin Shan, Yongjun Dang, Zhe Zhao, Lemin Zheng, Weiguo Fu, Lixin Wang. Downregulation of RhoA/ROCK1/YAP/F-actin causing decreased aortic smooth muscle cell stiffness promotes aortic dissection formation. Life Metabolism, 2024, 3(5): loae022 https://doi.org/10.1093/lifemeta/loae022

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