Promising dawn in the management of pulmonary hypertension: The mystery veil of gut microbiota
Yicheng Yang , Hanwen Zhang , Yaoyao Wang , Jing Xu , Songren Shu , Peizhi Wang , Shusi Ding , Yuan Huang , Lemin Zheng , Yuejin Yang , Changming Xiong
iMeta ›› 2024, Vol. 3 ›› Issue (2) : 159
Promising dawn in the management of pulmonary hypertension: The mystery veil of gut microbiota
•The significant development in gut microbiota has brought an unprecedented paradigm for pulmonary hypertension (PH) management in recent years, which has delighted researchers and clinicians in precise disease control. •The gut–lung axis is the bidirectional interaction between the gut and lung, which occurs through circulation, the nervous system, and other physiological processes, ultimately affecting the health of both the gut and the lung. •We provided a comprehensive landscape of gut microbiota and its associated metabolites in PH, emphasizing the interplay between microorganisms and hosts in modulating PH. •With the rapid development of technologies, including metagenomic and metabolomics on gut microbiota, the association of microorganisms and the human body will be untangled eventually, which will bring the dawn for disease cure followed by prognosis improvement among patients with PH.
disease management / gut–lung axis / gut microbiota / metabolites / pulmonary hypertension
2024 The Authors. iMeta published by John Wiley & Sons Australia, Ltd on behalf of iMeta Science.
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