Antibacterial hydroxyapatite coatings on titanium dental implants

Abstract

Titanium and its alloys are often used as substrates for dental implants due to their excellent mechanical properties and good biocompatibility. However, their ability to bind to neighboring bone is limited due to the lack of biological activity. At the same time, they show poor antibacterial ability which can easily cause bacterial infection and chronic inflammation, eventually resulting in implant failure. The preparation of composite hydroxyapatite coatings with antibacterial ability can effectively figure out these concerns. In this review, the research status and development trends of antibacterial hydroxyapatite coatings constructed on titanium and its alloys are analyzed and reviewed. This review may provide valuable reference for the preparation and application of high-performance and multi-functional dental implant coatings in the future.

Graphical abstract

Keywords

composite / dental implant / hydroxyapatite / titanium / antibacterial

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Disclosure of potential conflicts of interests

The authors declare that they have no competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Acknowledgements

This work was supported by the National Natural Science Foundation of China (Grant Nos. 12272253, 11632013, and 11902214) and the Shanxi-Zheda Institute of Advanced Materials and Chemical Engineering (Grant Nos. 2021SX-AT008 and 2021SX-AT009). The support of the Fund Program for the Scientific Activities of Selected Returned Overseas Professionals in Shanxi Province (Grant No. 20220006) is also acknowledged with gratitude. Thanks to BioRender for help on some pictures.

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