Nanodiamonds as nanomaterial for biomedical field

Abstract

Recent advances in nanotechnology have attracted significant attention to nanodiamonds (NDs) in both industrial and research areas thanks to their remarkable intrinsic properties: large specific area, poor cytotoxicity, chemical resistance, magnetic and optical properties, ease of large-scale production, and surface reactivity make them suitable for numerous applications, including electronics, optics, sensors, polishing materials, and more recently, biological purposes. Growing interest in diamond platforms for bioimaging and chemotherapy is observed. Given the outstanding features of these particles and their ease of tuning, current and future applications in medicine have the potential to display innovative imaging applications and to be used as tools for monitoring and tracking drug delivery in vivo.

Graphical abstract

Keywords

nanodiamond / scale-up synthesis / bioimaging / hyperpolarization / drug delivery

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Disclosure of potential conflicts of interest

The authors declare that they have no conflict of interest.

Acknowledgements

The authors thank the Center for Microscopy and Molecular Imaging (CMMI, supported by the European Regional Development Fund and Wallonia), the Fond National de la Recherche Scientifique (FNRS), the Actions de Recherche Concertées (ARC) programs of the French Community of Belgium, COST actions and the Walloon region. The authors would like to acknowledge the Interuniversity Attraction Poles of the Belgian Federal Science Policy Office and the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 863099.

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