Blood compatibility of zinc–calcium phosphate conversion coating on Mg–1.33Li–0.6Ca alloy

Abstract

Magnesium alloys as a new class of biomaterials possess biodegradability and biocompatibility in comparison with currently used metal implants. However, their rapid corrosion rates are necessary to be manipulated by appropriate coatings. In this paper, a new attempt was used to develop a zinc–calcium phosphate (Zn–Ca–P) conversion coating on Mg–1.33Li–0.6Ca alloys to increase the biocompatibility and improve the corrosion resistance. In vitro blood biocompatibility of the alloy with and without the Zn–Ca–P coating was investigated to determine its suitability as a degradable medical biomaterial. Blood biocompatibility was assessed from the hemolysis test, the dynamic cruor time test, blood cell count and SEM observation of the platelet adhesion to membrane surface. The results showed that the Zn–Ca–P coating on Mg–1.33Li–0.6Ca alloys had good blood compatibility, which is in accordance with the requirements for medical biomaterials.

Keywords

magnesium alloy / lithium / zinc–calcium phosphate coating / biocompatibility / biomaterial

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