Green synthesis of biocompatible gold nanoparticles using Fagopyrum esculentum leaf extract

Abstract

This report describes the use of ethnolic extract of Fagopyrum esculentum leaves for the synthesis of gold nanoparticles. UV-visible spectroscopy analysis indicated the successful formation of gold nanoparticles. The synthesized nanoparticles were characterized by transmission electron microscopy (TEM), high resolution TEM (HRTEM) and were found to be spherical, hexagonal and triangular in shape with an average size of 8.3 nm. The crystalline nature of the gold nanoparticles was confirmed from X-ray diffraction (XRD) and selected-area electron diffraction (SAED) patterns. Fourier transform infrared (FT-IR) and energy-dispersive X-ray analysis (EDX) suggested the presence of organic biomolecules on the surface of the gold nanoparticles. Cytotoxicity tests against human HeLa, MCF-7 and IMR-32 cancer cell lines revealed that the gold nanoparticles were non-toxic and thus have potential for use in various biomedical applications.

Keywords

biomaterials / crystal growth / electron microscopy / Fourier transform infrared spectroscopy / adsorption