Synthesis and characterization of biodegradable polyurethane based on poly(?-caprolactone) and L-lysine ethyl ester diisocyanate

Jian HAN, Bing CHEN, Lin YE, Ai-ying ZHANG, Jian ZHANG, Zeng-guo FENG

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PDF(282 KB)
Front. Mater. Sci. ›› 2009, Vol. 3 ›› Issue (1) : 25-32. DOI: 10.1007/s11706-009-0013-4
RESEARCH ARTICLE

Synthesis and characterization of biodegradable polyurethane based on poly(?-caprolactone) and L-lysine ethyl ester diisocyanate

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Abstract

A biocompatible diisocyanate, lysine ethyl ester diisocyanate, was prepared. Afterwards, biodegradable polyurethane (PU) was synthesized by the step-growth polymerization of this diisocyanate with hydroxyl terminated poly(ϵ-caprolactone) in the presence of 1,4-butanediol as a chain-extender. The resulting PU was characterized by GPC, IR and DSC measurements. Its mechanical strength was found to increase with increasing the hard segment content. The PU microfiber meshes with high porosity were obtained by solution electrospinning technique. Their degradation behavior in the PBS and enzymatic solution was also investigated.

Keywords

polyurethane / biodegradability / poly(ϵ-caprolactone) / L-lysine ethyl ester diisocyanate / solution electrospinning

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Jian HAN, Bing CHEN, Lin YE, Ai-ying ZHANG, Jian ZHANG, Zeng-guo FENG. Synthesis and characterization of biodegradable polyurethane based on poly(ϵ-caprolactone) and L-lysine ethyl ester diisocyanate. Front Mater Sci Chin, 2009, 3(1): 25‒32 https://doi.org/10.1007/s11706-009-0013-4

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Acknowledgements

This work was in part supported by the “863”βProject of the Ministry of Science and Technology of China (Grant No. 2007AA021905).

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2014 Higher Education Press and Springer-Verlag Berlin Heidelberg
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