Separation of gibberellic acid (GA3) by macroporous adsorption resins

Abstract

The adsorption effects of several macroporous adsorption resins for gibberellic acid (GA3) were investigated. The dynamic adsorption capacity is 58.38 mg/g dry beads for resin R4 and 96.46 mg/g dry beads for resin R5 which is consistent with the surface area. Aqueous methanol (50%, V/V) is a good eluent and the yield of GA3 is above 95%. The concentration of GA3 could increase five-fold after an adsorption-elution cycle and this is important when considering further crystallization of GA3 in an industrial process.

Keywords

gibberellic acid (GA3) / adsorption / macroporous adsorption resin / separation