Brain–Computer Interfaces: The Dawn of a New Era in Disease Treatment
Yuqi Feng , Wangzheqi Zhang , Jun Chen , Huang Wu , Lei Wu , Yanhao Qiu , Xiaoming Deng , Chenglong Zhu , Yisheng Chen , Zhijie Zhao , Changli Wang , Xiaomin Zhang
Exploration ›› 2026, Vol. 6 ›› Issue (3) : 20250452
Brain–computer interface (BCI) technology has emerged as a crucial interdisciplinary advancement in the field of neuropsychiatric disease treatment. With the global rise in the prevalence of neurological and psychiatric disorders, which impose a substantial burden on society, BCI offers a novel approach. Since the discovery of bioelectric phenomena in the 19th century, various classification frameworks have been developed based on signal paradigms, invasiveness, and feedback mechanisms. BCI applications span multiple disease areas. In movement disorders, it aids in restoring motor function through prosthetic control, functional electrical stimulation, and brain stimulation–based therapies. For patients with communication barriers, it enables alternative communication methods and speech-related neural signal decoding. In psychiatric conditions, BCI shows growing potential in both diagnosis and treatment, particularly in conditions like autism and depression. Despite significant progress, BCI faces challenges. The long-term biocompatibility of electrodes and the resolution of neural signals remain to be improved. To address these limitations, research on new electrode materials, such as carbon nanomaterials and composites, is ongoing. Emerging BCI technologies, including endovascular BCI and optogenetics BCI, present new possibilities. The integration of multimodal technologies and artificial intelligence in BCI systems is expected to enhance performance and enable more personalized treatment. Overall, BCI technology holds great promise for improving the quality of life of patients with neuropsychiatric disorders and driving innovation in the medical and neuroscience fields.
brain–computer interface / communication barriers / electrode materials / movement disorders / neuropsychiatric disorders / psychiatric disorders
| [1] |
Institute of Health Metrics and Evaluation. Global Health Data Exchange (GHDx) (2021). |
| [2] |
|
| [3] |
|
| [4] |
|
| [5] |
|
| [6] |
|
| [7] |
|
| [8] |
|
| [9] |
|
| [10] |
|
| [11] |
|
| [12] |
|
| [13] |
|
| [14] |
|
| [15] |
|
| [16] |
|
| [17] |
|
| [18] |
|
| [19] |
|
| [20] |
|
| [21] |
|
| [22] |
|
| [23] |
|
| [24] |
|
| [25] |
|
| [26] |
|
| [27] |
|
| [28] |
|
| [29] |
|
| [30] |
|
| [31] |
|
| [32] |
|
| [33] |
|
| [34] |
|
| [35] |
|
| [36] |
|
| [37] |
|
| [38] |
|
| [39] |
|
| [40] |
|
| [41] |
|
| [42] |
|
| [43] |
|
| [44] |
|
| [45] |
|
| [46] |
|
| [47] |
WMU Student Scientific Circle at the Department of Neurosurgery, WMU Department of Neurosurgery, and WMU Department of Neurosurgery, Poland, “Methods of Integrating the Human Nervous System With Electronic Circuits,” Advances in Clinical and Experimental Medicine 28 (2019): 1125–1135, https://doi.org/10.17219/acem/103414. |
| [48] |
|
| [49] |
|
| [50] |
|
| [51] |
|
| [52] |
|
| [53] |
|
| [54] |
|
| [55] |
|
| [56] |
|
| [57] |
|
| [58] |
|
| [59] |
|
| [60] |
|
| [61] |
|
| [62] |
|
| [63] |
|
| [64] |
|
| [65] |
|
| [66] |
|
| [67] |
|
| [68] |
|
| [69] |
|
| [70] |
|
| [71] |
|
| [72] |
|
| [73] |
|
| [74] |
|
| [75] |
|
| [76] |
|
| [77] |
|
| [78] |
|
| [79] |
|
| [80] |
|
| [81] |
|
| [82] |
|
| [83] |
|
| [84] |
|
| [85] |
|
| [86] |
|
| [87] |
|
| [88] |
|
| [89] |
|
| [90] |
|
| [91] |
|
| [92] |
|
| [93] |
|
| [94] |
|
| [95] |
|
| [96] |
|
| [97] |
|
| [98] |
|
| [99] |
|
| [100] |
|
| [101] |
|
| [102] |
|
| [103] |
|
| [104] |
|
| [105] |
|
| [106] |
|
| [107] |
|
| [108] |
|
| [109] |
|
| [110] |
|
| [111] |
|
| [112] |
|
| [113] |
|
| [114] |
|
| [115] |
|
| [116] |
|
| [117] |
|
| [118] |
|
| [119] |
|
| [120] |
|
| [121] |
|
| [122] |
|
| [123] |
|
| [124] |
|
| [125] |
|
| [126] |
|
| [127] |
|
| [128] |
|
| [129] |
|
| [130] |
|
| [131] |
|
| [132] |
|
| [133] |
|
| [134] |
|
| [135] |
|
| [136] |
|
| [137] |
|
| [138] |
|
| [139] |
|
| [140] |
|
| [141] |
|
| [142] |
|
| [143] |
|
| [144] |
|
| [145] |
|
| [146] |
|
| [147] |
|
| [148] |
|
| [149] |
|
| [150] |
|
| [151] |
|
| [152] |
|
| [153] |
|
| [154] |
|
| [155] |
|
| [156] |
|
| [157] |
|
| [158] |
|
| [159] |
|
| [160] |
|
| [161] |
|
| [162] |
|
| [163] |
|
| [164] |
|
| [165] |
|
| [166] |
|
| [167] |
|
| [168] |
|
| [169] |
|
| [170] |
|
| [171] |
|
| [172] |
|
| [173] |
|
| [174] |
|
| [175] |
|
| [176] |
|
| [177] |
|
| [178] |
|
| [179] |
|
| [180] |
|
| [181] |
|
| [182] |
|
| [183] |
|
| [184] |
|
| [185] |
|
| [186] |
|
| [187] |
|
| [188] |
|
| [189] |
|
| [190] |
|
| [191] |
|
| [192] |
|
| [193] |
|
| [194] |
|
| [195] |
|
| [196] |
|
| [197] |
|
| [198] |
|
| [199] |
|
| [200] |
|
| [201] |
|
| [202] |
|
| [203] |
|
| [204] |
|
| [205] |
|
| [206] |
|
| [207] |
|
| [208] |
|
| [209] |
|
| [210] |
|
| [211] |
|
| [212] |
|
| [213] |
|
| [214] |
|
| [215] |
|
| [216] |
|
| [217] |
|
| [218] |
|
| [219] |
|
| [220] |
|
| [221] |
|
| [222] |
|
| [223] |
|
| [224] |
|
| [225] |
|
| [226] |
|
| [227] |
|
| [228] |
|
| [229] |
|
| [230] |
|
| [231] |
|
| [232] |
|
| [233] |
|
| [234] |
|
| [235] |
|
| [236] |
|
| [237] |
|
| [238] |
|
| [239] |
|
| [240] |
|
| [241] |
|
| [242] |
|
| [243] |
|
| [244] |
|
| [245] |
|
| [246] |
|
| [247] |
|
| [248] |
|
| [249] |
|
| [250] |
|
| [251] |
|
| [252] |
|
| [253] |
|
| [254] |
|
| [255] |
|
| [256] |
|
| [257] |
|
| [258] |
|
| [259] |
|
| [260] |
|
| [261] |
|
| [262] |
|
| [263] |
|
| [264] |
|
| [265] |
|
| [266] |
|
| [267] |
|
| [268] |
|
| [269] |
|
| [270] |
|
| [271] |
|
| [272] |
|
| [273] |
|
| [274] |
|
| [275] |
|
| [276] |
|
| [277] |
|
| [278] |
|
| [279] |
|
| [280] |
|
| [281] |
|
| [282] |
|
| [283] |
|
| [284] |
|
| [285] |
|
| [286] |
|
| [287] |
|
| [288] |
|
| [289] |
|
| [290] |
|
| [291] |
|
| [292] |
|
| [293] |
|
| [294] |
|
| [295] |
|
| [296] |
|
| [297] |
|
| [298] |
|
| [299] |
|
| [300] |
|
| [301] |
|
| [302] |
|
| [303] |
|
| [304] |
|
| [305] |
|
| [306] |
|
| [307] |
|
| [308] |
|
| [309] |
|
| [310] |
|
| [311] |
|
| [312] |
|
| [313] |
|
| [314] |
|
| [315] |
|
| [316] |
|
| [317] |
|
| [318] |
|
| [319] |
|
| [320] |
|
| [321] |
|
| [322] |
|
| [323] |
|
| [324] |
|
| [325] |
|
| [326] |
|
| [327] |
|
| [328] |
|
| [329] |
|
| [330] |
|
| [331] |
|
| [332] |
|
| [333] |
|
| [334] |
|
| [335] |
|
| [336] |
|
| [337] |
|
| [338] |
|
| [339] |
|
| [340] |
|
| [341] |
|
| [342] |
|
| [343] |
|
| [344] |
|
| [345] |
|
| [346] |
|
| [347] |
|
| [348] |
|
| [349] |
|
| [350] |
|
| [351] |
|
| [352] |
|
| [353] |
|
| [354] |
|
| [355] |
|
| [356] |
|
| [357] |
S. o. P. Instrument, T. U. Opto-electronics Engineering, A. o. M. Engineering, T. Translational Medicine, TianJin University, Sheng wu yi xue gong cheng xue za zhi (Journal of Biomedical Engineering) 36 (2019), 856. |
| [358] |
|
| [359] |
|
| [360] |
|
2026 The Author(s). Exploration published by Henan University and John Wiley & Sons Australia, Ltd.
/
| 〈 |
|
〉 |