Anti-inflammatory Agent No. 6 is an effective preparation in treating many infectious diseases. It is made from Chinese medicinal herbs according to Traditional Chinese Medicine (TCM) theories. A rabbit model of DIC was established by injecting endotoxin of colibacilli. The mentioned agent was then administered to this model to observe its inhibitory action on the pathophysiological processes of DIC. The mechanism of its action might be the result of direct effect of degradation on endotoxin and intensification of phagocytosis of MPS. Thus, in TCM theory so-called “heat clearing and detoxifying properties” can be preliminarily interpreted by modern scientific investigations.