Avocado Oil: Recent Advances in Its Anti-diabetic Potential

Abstract

Background

Diet plays a crucial role in insulin resistance and diabetes, with high-fat and high-carbohydrate diets being major contributors. However, the type of fat consumed is critical, as different fatty acids impact insulin sensitivity differently.

Objective

This review examines the potential benefits of avocado oil, which is rich in monounsaturated fatty acids (MUFAs), in improving glycaemic control and lipid metabolism. It also explores variations in avocado oil composition across different avocado cultivars.

Methods

Experimental and clinical studies were analysed to assess the metabolic effects of avocado oil. The impact of MUFAs on insulin sensitivity, lipid profiles, and metabolic health was reviewed, alongside the influence of fruit quality, maturity, and cultivar differences.

Results

Avocado oil may enhance glycaemic control and lipid metabolism, benefiting individuals with diabetes and hypercholesterolemia. However, its composition varies significantly across avocado variants such as Hass, Reed, Ettinger, and Fuerte, influencing its therapeutic properties.

Conclusion

Avocado oil’s high MUFA content offers promising metabolic benefits. Further research is needed to standardize its therapeutic application, considering cultivar-dependent variations in composition.

Keywords

Avocado oil / Diabetes / Oleic acid / Monounsaturated fatty acids / Insulin resistance

© The Author(s), under exclusive licence to Huazhong University of Science and Technology 2025

Acknowledgements Not applicable.

Author’s Contributions KJ and PM searched the literature, DD has written the manuscript, SC and TP edited the manuscript, and JG reviewed and supervised the entire work.

Funding No funding was received for writing this manuscript.

Availability of Data and Materials No such data are used.

Declarations

Conflict of Interests The authors declare that there is no conflict of interest.

Ethics Approval and Consent to Participate Not applicable.

Consent for publication Not applicable.

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