Improving DNA Data Capacity: Forensic Parameters and Genetic Structure Analysis of Jinjiang Han Population with the Microreader™ Y Prime Plus ID System

Lu-yao Li , De-qing Wu , Li-lan Yao , Feng Li , Chao Liu , Fu-quan Jia

Current Medical Science ›› 2022, Vol. 42 ›› Issue (2) : 462 -466.

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Current Medical Science ›› 2022, Vol. 42 ›› Issue (2) : 462 -466. DOI: 10.1007/s11596-022-2570-z
Article

Improving DNA Data Capacity: Forensic Parameters and Genetic Structure Analysis of Jinjiang Han Population with the Microreader™ Y Prime Plus ID System

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Abstract

Objective

Population genetic analysis based on genetic markers harbors valuable forensic applications. In this regard, it is informative and imperative to explore Han groups as they are the largest population of China. In particular, there is a largely underrepresented amount of information from recent decades regarding the southeast costal Han Chinese. Therefore, the aim of this study is to investigate the available genetic characteristics of the Han population living in the Jinjiang, Fujian Province, Southeastern China.

Methods

We sampled 858 saliva samples and used the commercially available Microreader™ Y Prime Plus ID System to identify population data of Y-short tandem repeat (STR) loci of this region.

Results

A total of 822 different haplotypes were observed. The overall haplotype diversity, discriminatory power and haplotype match probability were 0.9999, 0.9999 and 0.0012, respectively.

Conclusion

Our results showed that the Jinjiang Han population was closely genetically related to Han groups of China. Overall, we identified a set of 37 Y-STRs that are highly polymorphic, and that can provide meaningful information in forensic practice and human genetic research.

Keywords

forensic genetics / Y-short tandem repeat / Jinjiang Han / haplotype diversity / Microreader™ Y Prime Plus ID System

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Lu-yao Li, De-qing Wu, Li-lan Yao, Feng Li, Chao Liu, Fu-quan Jia. Improving DNA Data Capacity: Forensic Parameters and Genetic Structure Analysis of Jinjiang Han Population with the Microreader™ Y Prime Plus ID System. Current Medical Science, 2022, 42(2): 462-466 DOI:10.1007/s11596-022-2570-z

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