Potential Role of Akkermansia muciniphila in Parkinson’s Disease and Other Neurological/Autoimmune Diseases

Xin Fang , Fang-jun Li , Dao-jun Hong

Current Medical Science ›› 2021, Vol. 41 ›› Issue (6) : 1172 -1177.

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Current Medical Science ›› 2021, Vol. 41 ›› Issue (6) : 1172 -1177. DOI: 10.1007/s11596-021-2464-5
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Potential Role of Akkermansia muciniphila in Parkinson’s Disease and Other Neurological/Autoimmune Diseases

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Abstract

The composition of the gut microbiota, including Akkermansia muciniphila (A. muciniphila), is altered in many neurological diseases and may be involved in the pathophysiological processes of Parkinson’s disease (PD). A. muciniphila, a mucin-degrading bacterium, is a potential next-generation microbe that has anti-inflammatory properties and is responsible for keeping the body healthy. As the role of A. muciniphila in PD has become increasingly apparent, we discuss the potential link between A. muciniphila and various neurological diseases (including PD) in the current review.

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Akkermansia muciniphila / gut microbiota / neurological diseases / Parkinson’s disease

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Xin Fang, Fang-jun Li, Dao-jun Hong. Potential Role of Akkermansia muciniphila in Parkinson’s Disease and Other Neurological/Autoimmune Diseases. Current Medical Science, 2021, 41(6): 1172-1177 DOI:10.1007/s11596-021-2464-5

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