Kindergartens Reopening in the Period of Regular Epidemic Prevention and Control, Benefitial or Harmful?

Abstract

In the period of regular epidemic prevention and control of Coronavirus disease 2019 (COVID-19) in our country, work resumption has been fully advanced. But there are still new sporadic local cases and imported cases across the country. In this situation, whether kindergartens reopening will increase the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread still remains uncertain. We reviewed two pediatric patients with moderate COVID-19, collected the epidemiologic information and monitored the cycle threshold value of rectal specimen and the viral loads, and discussed the transmission of SARS-CoV-2 in pediatric patients and the virulence of feces in children with moderate COVID-19, in order to analyze the risk of kindergartens reopening.

References

[1] CucinottaD, VanelliM. WHO Declares COVID-19 a Pandemic. Acta biomed, 2020, 91(1): 157-160

[2] VelavanTP, MeyerCG. The COVID-19 epidemic. Trop Med Internat Health, 2020, 25(3): 278-280

[3] PaulesCI, MarstonHD, FauciAS. Coronavirus Infections-More Than Just the Common Cold. JAMA, 2020, 323(8): 707-708

[4] BaiY, YaoL, WeiT, et al.. Presumed Asymptomatic Carrier Transmission of COVID-19. JAMA, 2020, 323(14): 1406-1407

[5] ChanJFW, YuanS, KokKH, et al.. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet, 2020, 395(10223): 514-523

[6] LudvigssonJF. Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults. Acta Paediatr, 2020, 109(6): 1088-1095

[7] WeiM, YuanJ, LiuY, et al.. Novel Coronavirus Infection in Hospitalized Infants Under 1 Year of Age in China. JAMA, 2020, 323(13): 1313-1314

[8] LuX, ZhangL, DuH, et al.. SARS-CoV-2 Infection in Children. New Engl J Med, 2020, 382(17): 1663-1665

[9] TezerH, Bedir DemirdagT. Novel coronavirus disease (COVID-19) in children. Turk Med Scik, 2020, 50(SI-1): 592-603

[10] ZimmermannP, CurtisN. COVID-19 in Children, Pregnancy and Neonates: A Review of Epidemiologic and Clinical Features. Pediatr Infect Dis J, 2020, 39(6): 469-477

[11] BiQ, WuY, MeiS, et al.. Epidemiology and transmission of COVID-19 in 391 cases and 1286 of their close contacts in Shenzhen, China: a retrospective cohort study. Lancet Infect Dis, 2020, 20(8): 911-919

[12] XuY, LiX, ZhuB, et al.. Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding. Nat Med, 2020, 26(4): 502-505

[13] WölfelR, CormanVM, GuggemosW, et al.. Virological assessment of hospitalized patients with COVID-2019. Nature, 2020, 581(7809): 465-469

[14] QiuL, JiaoR, ZhangA, et al.. A Case of Critically Ill Infant of Coronavirus Disease 2019 with Persistent Reduction of T Lymphocytes. Pediatr Infect Dis J, 2020, 39(7): e87-e90

RIGHTS & PERMISSIONS

Huazhong University of Science and Technology