Characteristic of marrow culture and clinical relevance in leukemia with 8/21 translocation
Sun Guo-xian , Wang Bian-ming , Yang Ai-de , Yu Dong-jiao
Current Medical Science ›› 1989, Vol. 9 ›› Issue (4) : 228 -231.
Characteristic of marrow culture and clinical relevance in leukemia with 8/21 translocation
Karyotypes and in vitro cultures of bone marrow cells from eleven patients with acute myelogenous leukemia M2 type were performed. 8/21 translocation was found in 5 patients. In all of them the cultures in vitro shared one characteristic, i.e., clusters were small and less in number. These patients could relatively easily obtain complete remission. The similarity of CFU-GM in patients with t (8;2l) may be another important biological phenotype.
AML (M2) / t(8, 21) / CFU-GM growth pattern / biological phenotype
/
| 〈 |
|
〉 |
PDF
