Application of potassium titanyl phosphate (KTP) laser delivered via bronchofiberscope in the treatment of endobronchial tuberculosis

Abstract

To explore the application of potassium titanyl phosphate (KTP) laser delivered via bronchofiberscope in the treatment of endobronchial tuberculosis. 36 patients with a diagnosis of endobronchial tuberculosis, with age ranging from 15 to 40 y were treated with KTP, laser between Dec. 2002 and July 2004 (designated as treatment group). The other 36 patients diagnosed as having endobronchial tuberculosis (aged 18 to 42 y, with a mean age of 33.5 y) without having received KTP laser treatment were included in a control group. Our results showed that the effective rates, in terms of recovery of bronchial lumen and cleanup of caseous necrotic mass were significantly higher in the treatment group 8 weeks after the treatment (P<0.01), and the healing rates of atelectasis and obstructive infection were also significantly higher in the treatment group (P<0.05 andP<0.01), but the incidence of complication after 8 weeks was no significant difference (P<0.05). No significant changes were found in SaO₂ and HR before, during and after the operation in the treatment group (P>0.05). It is concluded that KTP laser is an effective therapy for endobronchial tuberculosis.

Keywords

KTP laser / bronchus / tuberculosis / bronchofiberoscope

References

[1] ZhaoH Z, LiuY N, WangJ X, et al. . Nd-YAG laser treated bronchial tuberculosis. Med J Chin PLA (Chinese), 1991, 16(5): 354-356

[2] ZhouM, JiaY M, ChenF Z, et al. . Nd³⁺: YAG laser treated endobronchial tuberculosis of entire obstructive endobronchial lumen by bronchofiberoscope. J Shanghai med Univer (Chinese), 1995, 22(1): 41-43

[3] MaiJ B. A bit thinks in the laser therapy. Chin J Laser Med & Surg (Chinese), 2004, 13(4): 269-269

[4] NakamuraH, KawasakiM, HiguchiY, et al. . Transnasal endoscopic resection of juvenile nasopharyngeal angiofibroma with KTP laser. Eur Arch Otorhinolaryngol, 1999, 256(4): 212-214

[5] PiatonJ M, LimonS, OunnasN, et al. . Transcanalicular endodacryocystorhinostomy using Neodymium: YAG laser. Fr Ophtalmol, 1994, 17(10): 555-567

[6] YiJ L, BaiY Q, XiongK Y. Compared KTP laser to rabbit lacrimal passage damage degree with Nd: YAG laser. Chinese Journal of Laser Medicine & Surgery (Chinese), 2003, 12: 9-11

[7] NishizakiK, KariyaS, FukushimaK, et al. . A novel laser-assisted stapedotomy technique for congenital stapes fixation. Int J Pediatr Otorhinolaryngol, 2004, 68(3): 341-345

[8] DawnG, GuptaG. Comparison of potassium titanyl phosphate vascular laser and hyfrecator in the treatment of vascular spiders and cherry angiomas. Clin Exp Dermatol, 2003, 28(6): 581-583

[9] LeeM W. Combination 532-nm and 1064-nm lasers for noninvasive skin rejuvenation and toning. Arch Dermatol, 2003, 139(10): 1265-1276

[10] HaiM A, MalekR S. Photoselective vaporization of the prostate: initial experience with a new 80W KTP laser for the treatment of benign prostatic hyperplasia. J Endourol, 2003, 17(2): 93-76

[11] JingQ S, LiC P, ZhouJ, et al. . Observed curative effect of KTP laser treating endobronchial tuberculosis by bronchofiberoscope in the near term. Chinese Journal of Laser Medicine & Surgery (Chinese), 2004, 13(2): 78-80

[12] YanB Y, DuanM H. Editor in chief, Phthisiologia, 2003, Peking, Peking Publishing Company (Chinese): 612-617